Udell J, Schumacher H R, Kaplan F, Fallon M D
Arthritis Rheum. 1986 Aug;29(8):1032-8. doi: 10.1002/art.1780290815.
We describe a 27-year-old man with familial acroosteolysis involving 9 fingers. Bone biopsy of an affected digit showed osteolysis with no tetracycline deposition, rare osteoclasts, increased vascularity, and numerous mast cells. In contrast, the iliac crest bone showed active bone remodeling and normal double-tetracycline labeling. We believe mast cells deserve further study as possible factors in this form of localized osteolysis.
我们描述了一名27岁患有家族性肢端骨质溶解症累及9根手指的男性。对一根受累手指进行骨活检显示骨质溶解，无四环素沉积，破骨细胞罕见，血管增多，且有大量肥大细胞。相比之下，髂嵴骨显示有活跃的骨重塑和正常的双四环素标记。我们认为肥大细胞作为这种局限性骨质溶解症的可能因素值得进一步研究。
