Gokool Vidia A, Holness Howard K, Furton Kenneth G
Florida International University, Department of Chemistry and Biochemistry, 11200 SW 8th Street, Miami, FL 33199, United States; Florida International University, Global Forensic and Justice Center, 11200 SW 8th Street, Miami, FL 33199, United States.
Forensic Sci Int. 2022 May;334:111235. doi: 10.1016/j.forsciint.2022.111235. Epub 2022 Feb 17.
A dual effort investigation was conducted to study (a) the naturally occurring variation in same-donor human hand odor samples over time and (b) the accuracy in associating same-donor human hand odor samples. Hand odor samples were collected from 8 donors throughout 5 sampling sessions; samples were collected in triplicate and analyzed by HS-SPME-GC-MS at each sampling session. The resulting human hand odor profiles were analyzed to investigate (a) the variability of human hand odor profiles as a function of time and (b) the ability to determine the source origin of human hand odor samples, determining samples to be from the same source or different sources. The researchers observed greater variation in 2-dimensional human scent profile patterning schemes among inter-day, inter-subject samples and less variation in inter-day, intra-subject samples. Although intra-subject samples revealed less variation than inter-subject samples, there was still notable variability among inter-day, intra-subject human scent profiles, with an observed time dependency. Two proof of concept models for the source determination of human hand odor samples were developed with maximum performance measuring TPR = 0.817/ FPR = 0.308 and TPR = 1.000/ FPR = 0.206 for models one and two, respectively. The study quantified same-donor human hand odor profile variation over time displayed within a larger goal of determining sample source origin.
开展了一项双方面的研究，以探讨：(a) 同一供体的人类手部气味样本随时间的自然变化情况；(b) 关联同一供体的人类手部气味样本的准确性。在5个采样时段从8名供体采集了手部气味样本；每个采样时段的样本均采集一式三份，并通过顶空固相微萃取-气相色谱-质谱联用仪进行分析。对所得的人类手部气味图谱进行分析，以研究：(a) 人类手部气味图谱随时间变化的变异性；(b) 确定人类手部气味样本来源的能力，即确定样本是来自同一来源还是不同来源。研究人员观察到，日间、个体间样本的二维人类气味图谱模式变化更大，而日间、个体内样本的变化较小。虽然个体内样本的变化小于个体间样本，但日间、个体内人类气味图谱之间仍存在显著变异性，且存在时间依赖性。开发了两种用于确定人类手部气味样本来源的概念验证模型，模型一和模型二的最大性能指标分别为真阳性率（TPR）=0.817/假阳性率（FPR）=0.308和TPR=1.000/FPR=0.206。该研究在确定样本来源这一更大目标范围内，量化了同一供体的人类手部气味图谱随时间的变化情况。
