Perhoniemi V, Linko K
Eur Urol. 1986;12(4):244-8. doi: 10.1159/000472628.
In a prospective clinical study we compared the hemodynamics and clinical symptoms following regional blocks and general anesthesia. 115 patients undergoing transurethral resection of the prostate were randomized to spinal (n = 62) and epidural (n = 53) blocks. An additional 10 patients received general anesthesia. Calf arterial flow, determined by strain gauge plethysmography (SGP), was similar pre- and postoperatively in the regional block groups but decreased in the general anesthesia group (p less than 0.05) on the 5th postoperative day compared to the preoperative day. On the 2nd and 5th postoperative days, venous capacity was lower (p less than 0.05) after general anesthesia compared to regional blocks. Antiembolism stockings offered no hemodynamic or clinical advantages. During the hospital stay (screening by Doppler and SGP) and 3 months of follow-up, no deep vein thrombosis or pulmonary embolism was diagnosed. 3 months after the operation, unspecific pain and/or weakness in the legs were reported by 12 patients in the spinal group, while the epidural group remained asymptomatic (p less than 0.01). We conclude that the predictive value of negative Doppler and SGP findings is good and that spinal and epidural blocks are hemodynamically advantageous as compared to general anesthesia.
在一项前瞻性临床研究中,我们比较了区域阻滞和全身麻醉后的血流动力学及临床症状。115例行经尿道前列腺切除术的患者被随机分为脊髓麻醉组(n = 62)和硬膜外麻醉组(n = 53)。另外10例患者接受全身麻醉。通过应变片体积描记法(SGP)测定的小腿动脉血流,区域阻滞组术前和术后相似,但全身麻醉组术后第5天与术前相比有所下降(p < 0.05)。术后第2天和第5天,全身麻醉后的静脉容量低于区域阻滞(p < 0.05)。抗栓袜未显示出血流动力学或临床优势。在住院期间(通过多普勒和SGP筛查)及3个月的随访中,未诊断出深静脉血栓形成或肺栓塞。术后3个月,脊髓麻醉组有12例患者报告腿部出现非特异性疼痛和/或无力,而硬膜外麻醉组仍无症状(p < 0.01)。我们得出结论,多普勒和SGP检查结果为阴性的预测价值良好,与全身麻醉相比,脊髓麻醉和硬膜外麻醉在血流动力学方面具有优势。