Perhoniemi V, Linko K
Acta Anaesthesiol Scand. 1987 Feb;31(2):117-21. doi: 10.1111/j.1399-6576.1987.tb02532.x.
Changes in the haemodynamics of the lower extremities, big toe temperature, blood pressure and heart rate were studied in 20 patients undergoing spinal or epidural anaesthesia for transurethral surgery. Calf blood flow was determined by strain gauge plethysmography (SGP) and Doppler ultrasound. Bupivacaine 0.5% was injected at the L3-L4 interspace, the dose being 3-4 ml (mean 3.6) in the spinal and 17-20 ml (mean 18.6) in the epidural group. The number of sensory blocked segments 30 min after anaesthesia was 12.7 +/- 0.7 (mean +/- s.e.mean) and 14.4 +/- 0.7, respectively. Only minor decreases in blood pressure were noted following the blocks. Heart rate remained virtually unchanged. The increase in skin temperature was more pronounced (P less than 0.01) following epidural (mean 8 degrees C) than spinal anaesthesia (mean 4 degrees C). In addition, the arterial blood flow was significantly higher (P less than 0.05) following epidural than spinal block (means 3.5 and 2.2 ml/100 ml/min, respectively). The venous capacity and maximum venous outflow remained practically unchanged in both groups. Obviously, epidural anaesthesia with bupivacaine causes a more intensive sympathetic block than does spinal anaesthesia. As probably no venous pooling occurred, when examined by SGP and Doppler ultrasound, neither of the blocks is likely to contribute to the initiation of deep vein thrombosis.
对20例接受脊髓或硬膜外麻醉以进行经尿道手术的患者,研究其下肢血流动力学、大脚趾温度、血压和心率的变化。小腿血流量通过应变片体积描记法(SGP)和多普勒超声测定。在L3-L4间隙注射0.5%布比卡因,脊髓组剂量为3-4 ml(平均3.6 ml),硬膜外组为17-20 ml(平均18.6 ml)。麻醉后30分钟感觉阻滞节段数分别为12.7±0.7(平均±标准误)和14.4±0.7。阻滞之后仅观察到血压有轻微下降。心率基本保持不变。硬膜外麻醉后皮肤温度升高更明显(P<0.01)(平均8℃),高于脊髓麻醉(平均4℃)。此外,硬膜外麻醉后动脉血流量显著高于脊髓阻滞(P<0.05)(分别为平均3.5和2.2 ml/100 ml/min)。两组的静脉容量和最大静脉流出量基本保持不变。显然,布比卡因硬膜外麻醉比脊髓麻醉引起的交感神经阻滞更强。由于通过SGP和多普勒超声检查时可能未发生静脉淤血,两种阻滞都不太可能导致深静脉血栓形成。