Foate J A, Horton H, Davis F M
Anaesth Intensive Care. 1985 Nov;13(4):383-6. doi: 10.1177/0310057X8501300409.
Using venous occlusion impedance plethysmography, leg blood flow was measured in seventeen men undergoing transurethral prostatectomy under either amethocaine spinal anaesthesia (SAB) or nitrous oxide-halothane general anaesthesia (GA). Mean leg blood flow doubled (206% of pre-operative control value) following induction of SAB, remained elevated throughout surgery (146% of control at the end of operation) and had returned to pre-operative levels (94%) by two hours postoperatively. Under GA, mean blood flow rose gradually during surgery to 136% of control by the end. However, mean blood flow was only 28% of control at one hour postoperatively, rising to 66% of control by two hours. Analysis of variance showed a significant difference in blood flow changes between the two groups (Greenhouse Geisser P = 0.005). The early postoperative fall in leg blood flow in the GA group might be important in the aetiology of postoperative deep vein thrombosis.
采用静脉阻塞阻抗体积描记法，对17名接受经尿道前列腺切除术的男性患者在蛛网膜下腔麻醉（SAB）下使用丁卡因或在氧化亚氮 - 氟烷全身麻醉（GA）下进行腿部血流测量。蛛网膜下腔麻醉诱导后，平均腿部血流增加一倍（为术前对照值的206%），在整个手术过程中一直升高（手术结束时为对照值的146%），术后两小时恢复到术前水平（94%）。在全身麻醉下，平均血流在手术过程中逐渐上升，到手术结束时达到对照值的136%。然而，术后一小时平均血流仅为对照值的28%，两小时时升至对照值的66%。方差分析显示两组血流变化存在显著差异（Greenhouse Geisser P = 0.005）。全身麻醉组术后早期腿部血流下降可能在术后深静脉血栓形成的病因中起重要作用。
