Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, 646000, Sichuan, China.
Department of Orthopedic Surgery, Affiliated Hospital of Southwest Medical University, No. 25 of Taiping Road, Luzhou, 646000, Sichuan, China.
BMC Musculoskelet Disord. 2022 Mar 11;23(1):236. doi: 10.1186/s12891-022-05177-0.
Anterior debridement, decompression, bone grafting, and instrumentation are safe and effective techniques for patients with lower cervical spine tuberculosis. However, there is no consensus regarding the methods for using autogenous bone grafts. The purpose of this retrospective study was to compare the clinical outcomes of anterior surgical management for cervical spine tuberculosis by using an iliac bone graft versus a structural manubrium graft.
From January 2009 to September 2018, 23 patients with cervical spine tuberculosis were treated with anterior debridement, autogenous structural bone grafting and fixation at our spinal department. The patients were divided into 2 groups according to the different graft materials, namely, iliac crest bone grafts (Group A) and structural manubrium grafts (Group B). The clinical and radiographic results of the 2 groups were analyzed and compared.
The mean duration of follow-up was 24 months. Bony fusion was achieved in all patients without failure of internal fixation. There were no significant differences between the two groups with respect to the operation time, blood loss, fusion time, neurological outcomes, or postoperative local Cobb angle (P > .05). However, the donor site complication rate in Group A was greater than that in Group B. The postoperative ambulation time in Group A was later than that in Group B. The mean visual analog scale (VAS) score for donor site pain in Group A was higher than that in Group B at 1 week after surgery (P < 0.05). However, there was no significant difference between the 2 groups at the last visit (P > .05).
Both iliac bone grafts and sternal manubrium grafts can effectively reconstruct anterior column defects in anterior surgery. However, structural sternal manubrium autografts cause fewer complications associated with donor site morbidities than iliac bone grafts.
前路清创、减压、植骨和内固定是治疗下颈椎结核患者的安全有效的方法。然而,对于自体骨移植物的使用方法尚未达成共识。本回顾性研究的目的是比较使用髂骨移植物和结构性胸骨柄移植物进行颈椎结核前路手术治疗的临床结果。
自 2009 年 1 月至 2018 年 9 月,我院脊柱科对 23 例颈椎结核患者采用前路清创、自体结构性骨移植和固定治疗。根据不同的移植物材料将患者分为两组,即髂嵴骨移植物组(A 组)和结构性胸骨柄移植物组(B 组)。分析比较两组的临床和影像学结果。
平均随访时间为 24 个月。所有患者均获得骨性融合,无内固定失败。两组患者在手术时间、出血量、融合时间、神经功能结果和术后局部 Cobb 角方面无显著差异(P>0.05)。然而,A 组的供区并发症发生率高于 B 组。A 组术后下床活动时间晚于 B 组。A 组术后 1 周供区疼痛的视觉模拟评分(VAS)高于 B 组(P<0.05)。但两组在末次随访时无差异(P>0.05)。
髂骨和胸骨柄结构性自体移植物均可有效重建前路手术中的前柱缺损。然而,结构性胸骨柄自体移植物引起的供区并发症较髂骨移植物少。