Osuna J I, Pages I, Motiño M A, Rodriguez E, Osorio C
Horm Metab Res. 1986 Jul;18(7):473-5. doi: 10.1055/s-2007-1012349.
The cephalic phase of reflex insulin secretion was studied in normoglycemic and normoinsulinemic female patients, obese (more than 30% over IBW) and normal subjects. After an overnight fasting, at the sight of breakfast food, the obese group did not present a cephalic response. Their glycemia and insulinemia levels remained at base levels. One minute after visual and olfactory stimulation, a statistically significant rise in immunoreactive insulin levels which was maintained throughout the test, was observed in the control group.
在血糖正常和胰岛素水平正常的女性患者、肥胖者（超过理想体重30%）和正常受试者中研究了反射性胰岛素分泌的头期。经过一夜禁食后，看到早餐食物时，肥胖组未出现头期反应。他们的血糖和胰岛素水平维持在基础水平。在视觉和嗅觉刺激1分钟后，对照组观察到免疫反应性胰岛素水平有统计学意义的升高，且在整个测试过程中持续存在。
