Orthodontics, Division of Paediatric Dentistry and Orthodontics, Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong SAR, China.
Department of Dentistry and Oral Health, La Trobe University, 109 Arnold St., Bendigo, VIC, 3550, Australia.
Sci Rep. 2022 Mar 12;12(1):4318. doi: 10.1038/s41598-022-08293-y.
Midpalatal suture was analysed with cone beam computed tomography to identify its maturation with respect to age and maxillary-complex growth in 72 patients 9- to 21-year-old. Maxillary-complex was divided in premaxillary, maxillary, and palatine segment. Interdigitation and ossification of midpalatal suture, its density relative to hard tissues and soft tissues, and midpalatal suture density ratio were measured for each segment. Correlation of each parameter with age and maxillary-complex length was analysed, and classification trees were developed for staging parameters. Midpalatal suture maturation stages (MPSMS, from A to E) were applied to assess relationship with age and maxillary-complex length. Regarding age, ossification increased in maxillary segment of males (r = 0.39, p = 0.032), while suture density relative to soft tissues increased in maxillary (r = 0.37, p = 0.042) and palatine segments (r = 0.41, p = 0.027) of males and in palatine segment of females (r = 0.32, p = 0.041). In males, suture density relative to soft tissues discriminated two age-stages (p = 0.024), and the same parameter (p = 0.023) paired with ossification (p = 0.027) discriminated two length-stages. MPSMS identified length-differences between stage A and B in females (p = 0.001). Midpalatal-suture ossification and its density relative to soft tissues showed some relationship with age and maxillary-complex length, especially in males. However, challenging staging and limitations in the imaging method may limit clinical applications.
采用锥形束 CT 分析鼻中隔融合线，以明确其与年龄和上颌复合体生长的成熟度关系。将上颌复合体分为前颌段、上颌段和腭段。测量各段鼻中隔融合线的交错和骨化、相对于硬组织和软组织的密度，以及鼻中隔融合线密度比。分析每个参数与年龄和上颌复合体长度的相关性，并为各参数建立分级树。应用鼻中隔融合线成熟度分级（MPSMS，从 A 到 E）评估其与年龄和上颌复合体长度的关系。关于年龄，男性上颌段的骨化增加（r = 0.39，p = 0.032），而男性上颌段（r = 0.37，p = 0.042）和腭段（r = 0.41，p = 0.027）以及女性腭段鼻中隔融合线相对于软组织的密度增加（r = 0.32，p = 0.041）。在男性中，鼻中隔融合线相对于软组织的密度可区分两个年龄阶段（p = 0.024），同一参数（p = 0.023）与骨化（p = 0.027）联合可区分两个长度阶段。MPSMS 确定了女性 A 期和 B 期之间的长度差异（p = 0.001）。鼻中隔融合线的骨化及其相对于软组织的密度与年龄和上颌复合体长度有一定的关系，尤其是在男性中。然而，分级的挑战性和成像方法的局限性可能限制了临床应用。
