Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Cancer Sci. 2022 May;113(5):1722-1730. doi: 10.1111/cas.15329. Epub 2022 Mar 26.
Due to the increasing complexity of cancer treatment, ensuring safety and maintaining the quality of life during treatment are important issues. Patient-reported outcomes (PROs) in oncology are essential for assessing patient symptoms. A feasibility study was undertaken on breast cancer patients by building a PRO data collection system based on LINE, one of the most popular social network service applications in Japan. In this study, one or more predefined PRO questions for each breast cancer patient's clinical situation were sent to the patient's LINE application daily. The patient selected a predefined answer by tapping the screen, but no free-text answers were allowed. Seventy-three patients were enrolled. The median observation period was 435 days (84-656 days), and the total number of PROs collected was 16,417, with a mean of 224.9 reports per patient. Patients on adjuvant endocrine therapy were notified of 2.5 questions per week, and the median number of responses per week and response rate were 2.387 (1.687-11.627) and 95.5%, respectively. Analyzing the results by age group, the number of responses from those aged 60 and above was equal to or higher than that of the younger age group. It was also possible to track each patient's PROs accurately. These results suggested that the design of the system, based on an application used daily, instead of using specifically prepared applications for collecting electronic PROs, was the reason for the favorable acceptance from patients and the satisfactory response rate from all age groups, including the elderly.
由于癌症治疗的日益复杂性，确保治疗期间的安全性和维持生活质量是重要问题。肿瘤患者报告的结局（PROs）对于评估患者症状至关重要。本研究通过基于日本最受欢迎的社交网络服务应用程序之一 LINE 构建 PRO 数据采集系统，对乳腺癌患者进行了可行性研究。在这项研究中，每天向每位乳腺癌患者的 LINE 应用程序发送一个或多个针对其临床情况的预设 PRO 问题。患者通过点击屏幕选择预设答案，但不允许输入自由文本答案。共纳入 73 例患者。中位观察期为 435 天（84-656 天），共采集了 16417 份 PRO，每位患者的平均报告数为 224.9 份。接受辅助内分泌治疗的患者每周收到 2.5 个问题通知，每周的平均回复数和回复率分别为 2.387（1.687-11.627）和 95.5%。按年龄组分析结果，60 岁及以上患者的回复数量与年轻患者组相当或更高。此外，还可以准确跟踪每位患者的 PROs。这些结果表明，该系统的设计基于日常使用的应用程序，而不是使用专门用于收集电子 PROs 的应用程序，这是患者接受度良好和所有年龄段（包括老年人）均有满意回复率的原因。
