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奥马珠单抗成功治疗线性IgA/IgG大疱性皮肤病：一例报告

Linear IgA/IgG bullous dermatosis successfully treated with omalizumab: A case report.

作者信息

Haulrig Morten Bahrt, Nielsen Signe Ledou, Elberling Jesper, Skov Lone

机构信息

Department of Dermatology and Allergy Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark.

Department of Pathology, Herlev and Gentofte Hospital University of Copenhagen Herlev Denmark.

出版信息

Clin Case Rep. 2022 Mar 8;10(3):e05368. doi: 10.1002/ccr3.5368. eCollection 2022 Mar.

DOI:10.1002/ccr3.5368
PMID:35280104
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8905130/
Abstract

Linear IgA/IgG bullous dermatosis (LAGBD) is a rare, autoimmune blistering skin disease. We report a case of LAGBD in a 70-year-old woman. All common treatments were discontinued due to side effects or lack of treatment response. The patient was successfully treated with omalizumab which cleared her lesions after three months.

摘要

线状IgA/IgG大疱性皮肤病（LAGBD）是一种罕见的自身免疫性水疱性皮肤病。我们报告一例70岁女性的LAGBD病例。由于副作用或缺乏治疗反应，所有常用治疗均已停用。该患者使用奥马珠单抗成功治疗，三个月后皮疹消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbe9/8905130/8b7ffcee76fa/CCR3-10-e05368-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbe9/8905130/f95abf59ce96/CCR3-10-e05368-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbe9/8905130/8b7ffcee76fa/CCR3-10-e05368-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbe9/8905130/f95abf59ce96/CCR3-10-e05368-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbe9/8905130/8b7ffcee76fa/CCR3-10-e05368-g003.jpg

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Erratum:勘误：
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本文引用的文献

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High rates of severe disease and death due to SARS-CoV-2 infection in rheumatic disease patients treated with rituximab: a descriptive study.由于 SARS-CoV-2 感染，接受利妥昔单抗治疗的风湿性疾病患者出现严重疾病和死亡的比率较高：一项描述性研究。
Rheumatol Int. 2020 Dec;40(12):2015-2021. doi: 10.1007/s00296-020-04699-x. Epub 2020 Sep 18.
2
Increasing evidence for omalizumab in the treatment of bullous pemphigoid.越来越多的证据表明奥马珠单抗可用于治疗大疱性类天疱疮。
JAAD Case Rep. 2020 Feb 26;6(3):228-233. doi: 10.1016/j.jdcr.2020.01.002. eCollection 2020 Mar.
3
Linear IgA bullous dermatosis successfully treated with omalizumab: A case report.
奥马珠单抗成功治疗线性 IgA 大疱性皮肤病：一例报告
JAAD Case Rep. 2019 Oct 24;5(11):966-969. doi: 10.1016/j.jdcr.2019.08.019. eCollection 2019 Nov.
4
Erythrodermic linear IgA/IgG bullous dermatosis.红皮病型线性IgA/IgG大疱性皮肤病
Eur J Dermatol. 2019 Apr 1;29(2):220-221. doi: 10.1684/ejd.2019.3503.
5
Rituximab and Omalizumab for the Treatment of Bullous Pemphigoid: A Systematic Review of the Literature.利妥昔单抗和奥马珠单抗治疗大疱性类天疱疮：文献系统评价。
Am J Clin Dermatol. 2019 Apr;20(2):209-216. doi: 10.1007/s40257-018-0401-6.
6
Immunoglobulin E-Mediated Autoimmunity.免疫球蛋白 E 介导的自身免疫
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9
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10
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