Wu Chunxuan, Yan Jianhua, Li Wei
Department of Cardiology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Evid Based Complement Alternat Med. 2022 Mar 2;2022:6265198. doi: 10.1155/2022/6265198. eCollection 2022.
Acacetin (5,7-dihydroxy-4'-methoxyflavone) is the major bioactive component of the traditional Chinese medicine "Snow lotus". As a natural flavonoid compound, it has been shown to have good pharmacological effects such as anti-inflammatory, anticancer, and anti-obesity. Among them, its prominent role in cardiovascular diseases (CVD) has received extensive attention from scholars in recent years. In this review, the protective effects of acacetin on a variety of cardiovascular diseases, as well as the existing problems and prospects, are discussed and summarized. This review also highlights the great potential of acacetin, a natural-derived Chinese medicine, as a cardiovascular agent candidate.
刺槐素（5,7 - 二羟基 - 4'-甲氧基黄酮）是传统中药“雪莲”的主要生物活性成分。作为一种天然黄酮类化合物，它已被证明具有抗炎、抗癌和抗肥胖等良好的药理作用。其中，它在心血管疾病（CVD）中的突出作用近年来受到了学者们的广泛关注。在这篇综述中，讨论并总结了刺槐素对多种心血管疾病的保护作用以及存在的问题和前景。这篇综述还强调了刺槐素这种天然来源的中药作为心血管药物候选物的巨大潜力。
