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中度斑块状银屑病治疗中的差距:沙特皮肤科医生的一项调查。

Gaps in moderate plaque psoriasis management: A survey of Saudi dermatologists.

作者信息

Almohideb Mohammad, Almohideb Nora Abdulrahman

机构信息

Department of Dermatology, King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.

King Saud University Medical Intern, Riyadh, Saudi Arabia.

出版信息

J Family Med Prim Care. 2021 Dec;10(12):4519-4524. doi: 10.4103/jfmpc.jfmpc_1207_21. Epub 2021 Dec 27.

DOI:10.4103/jfmpc.jfmpc_1207_21
PMID:35280622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8884316/
Abstract

BACKGROUND

There are many barriers that usually lead to under-treatment of moderate psoriasis patients, with subsequent unsatisfactory results and clinical outcomes.

OBJECTIVE

Given this lack of consistent guidelines on treating moderate plaque psoriasis patients, the aim of the current study is to define how Saudi dermatologists define and treat such cases in the real-world clinical setting.

METHODS

We conducted an online cross-sectional survey from May 2020 to October 2020, involving all eligible dermatologists working at different academic, governmental, and private sectors in Saudi Arabia.

RESULTS

Finally, a total of 260 dermatologists were included in the final analysis; out of them, 140 (53.8%) were males and 120 (46.2%) were females. Regarding the tools used by participating dermatologists for diagnosis of moderate psoriasis, most of the participants (86.5%) used Body Surface Area (BSA), 7.3% used Physician Global Assessment (PGA), and 6.2% used Dermatology Life Quality Index (DLQI). Cutoff scores for defining moderate psoriasis varied widely among surveyed dermatologists. The surveyed dermatologists reported that 46% of their patients with moderate plaque psoriasis were receiving biologics as their primary therapy, while 24.1% were receiving prescription topical treatment, 20.3% were receiving an oral systemic therapy, 4.9% were using over-the-counter topical treatment, and 4.7% were receiving phototherapy.

CONCLUSION

There is a pervasive lack of consensus regarding the definition of moderate psoriasis, with reported wide ranges among the commonly used severity tools in psoriasis patients.

摘要

背景

存在许多障碍,通常导致中度银屑病患者治疗不足,进而产生不尽人意的结果和临床结局。

目的

鉴于在治疗中度斑块状银屑病患者方面缺乏一致的指南,本研究的目的是确定沙特皮肤科医生在实际临床环境中如何定义和治疗此类病例。

方法

我们在2020年5月至2020年10月进行了一项在线横断面调查,涉及在沙特阿拉伯不同学术、政府和私营部门工作的所有符合条件的皮肤科医生。

结果

最终,共有260名皮肤科医生纳入最终分析;其中,140名(53.8%)为男性,120名(46.2%)为女性。关于参与调查的皮肤科医生用于诊断中度银屑病的工具,大多数参与者(86.5%)使用体表面积(BSA),7.3%使用医生整体评估(PGA),6.2%使用皮肤病生活质量指数(DLQI)。在接受调查的皮肤科医生中,定义中度银屑病的临界值差异很大。接受调查的皮肤科医生报告称,他们46%的中度斑块状银屑病患者接受生物制剂作为主要治疗,而24.1%接受处方外用治疗,20.3%接受口服全身治疗,4.9%使用非处方外用治疗,4.7%接受光疗。

结论

对于中度银屑病的定义普遍缺乏共识,在银屑病患者常用的严重程度工具中报告的范围很广。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae42/8884316/5c7e26d4313a/JFMPC-10-4519-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae42/8884316/a3b4a0274175/JFMPC-10-4519-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae42/8884316/66a27e043fd4/JFMPC-10-4519-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae42/8884316/5c7e26d4313a/JFMPC-10-4519-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae42/8884316/a3b4a0274175/JFMPC-10-4519-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae42/8884316/66a27e043fd4/JFMPC-10-4519-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae42/8884316/5c7e26d4313a/JFMPC-10-4519-g003.jpg

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本文引用的文献

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Clin Rheumatol. 2020 Jun;39(6):1859-1869. doi: 10.1007/s10067-019-04870-1. Epub 2020 Jan 28.
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Patient perspectives on the pathway to psoriatic arthritis diagnosis: results from a web-based survey of patients in the United States.银屑病关节炎诊断途径的患者观点:来自美国一项针对患者的网络调查结果。
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Defining and treating moderate plaque psoriasis: a dermatologist survey.
定义和治疗中度斑块状银屑病:皮肤科医生调查
J Dermatolog Treat. 2018 Nov;29(7):658-663. doi: 10.1080/09546634.2018.1443200. Epub 2018 Mar 22.
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Efficacy and Safety of Apremilast in Patients With Moderate Plaque Psoriasis With Lower BSA: Week 16 Results from the UNVEIL Study.阿普司特治疗较低体表面积中度斑块状银屑病患者的疗效和安全性:UNVEIL研究第16周结果
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Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis.依奇珠单抗治疗中重度斑块状银屑病的 3 期临床试验。
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