Jawanda Manveen Kaur, Narula Ravi, Gupta Sonia, Gupta Priya
Department of Oral Pathology, Microbiology and Forensic Odontology, Laxmi Bai Institute of Dental Sciences and Hospital, Patiala, India.
Department of Oral and Maxillofacial Surgery, Guru Nanak Dev Dental College and Research Institute, Sunam, India.
J Oral Maxillofac Pathol. 2021 Sep-Dec;25(3):517-522. doi: 10.4103/jomfp.JOMFP_286_20. Epub 2022 Jan 11.
Polymorphous adenocarcinoma (PAC) is an uncommon tumor that affects minor salivary glands mainly. It presents as an indolent malignancy that frequently manifests as an asymptomatic, slow-growing mass within the oral cavity, especially palate and its clinical behavior resembles that of benign neoplasm, often causing delay in the diagnosis. Here, we report a rare case of PAC of palate in a 49-year-old female patient along with a concise review of characteristics of PAC and highlight diagnostic challenges caused by the overlap of clinical and microscopic features between PAC, pleomorphic adenoma and adenoid cystic carcinoma.
多形性腺癌(PAC)是一种罕见的肿瘤,主要累及小唾液腺。它表现为一种生长缓慢的恶性肿瘤,常表现为口腔内无症状、生长缓慢的肿块,尤其是腭部,其临床行为类似于良性肿瘤,常导致诊断延迟。在此,我们报告一例49岁女性患者腭部多形性腺癌的罕见病例,并简要回顾多形性腺癌的特征,强调多形性腺癌、多形性腺瘤和腺样囊性癌在临床和显微镜特征上的重叠所带来的诊断挑战。