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多形性腺癌:一例报告及其特征与诊断挑战

Polymorphous adenocarcinoma: A case report along with its characteristics and diagnostic challenges.

作者信息

Jawanda Manveen Kaur, Narula Ravi, Gupta Sonia, Gupta Priya

机构信息

Department of Oral Pathology, Microbiology and Forensic Odontology, Laxmi Bai Institute of Dental Sciences and Hospital, Patiala, India.

Department of Oral and Maxillofacial Surgery, Guru Nanak Dev Dental College and Research Institute, Sunam, India.

出版信息

J Oral Maxillofac Pathol. 2021 Sep-Dec;25(3):517-522. doi: 10.4103/jomfp.JOMFP_286_20. Epub 2022 Jan 11.

DOI:10.4103/jomfp.JOMFP_286_20
PMID:35281157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8859597/
Abstract

Polymorphous adenocarcinoma (PAC) is an uncommon tumor that affects minor salivary glands mainly. It presents as an indolent malignancy that frequently manifests as an asymptomatic, slow-growing mass within the oral cavity, especially palate and its clinical behavior resembles that of benign neoplasm, often causing delay in the diagnosis. Here, we report a rare case of PAC of palate in a 49-year-old female patient along with a concise review of characteristics of PAC and highlight diagnostic challenges caused by the overlap of clinical and microscopic features between PAC, pleomorphic adenoma and adenoid cystic carcinoma.

摘要

多形性腺癌(PAC)是一种罕见的肿瘤,主要累及小唾液腺。它表现为一种生长缓慢的恶性肿瘤,常表现为口腔内无症状、生长缓慢的肿块,尤其是腭部,其临床行为类似于良性肿瘤,常导致诊断延迟。在此,我们报告一例49岁女性患者腭部多形性腺癌的罕见病例,并简要回顾多形性腺癌的特征,强调多形性腺癌、多形性腺瘤和腺样囊性癌在临床和显微镜特征上的重叠所带来的诊断挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/ad8bf8e57917/JOMFP-25-517-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/651078c6a4cc/JOMFP-25-517-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/1fd191f9542e/JOMFP-25-517-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/54afb095d8ea/JOMFP-25-517-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/643882759961/JOMFP-25-517-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/e8d754d17354/JOMFP-25-517-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/ad8bf8e57917/JOMFP-25-517-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/651078c6a4cc/JOMFP-25-517-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/1fd191f9542e/JOMFP-25-517-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/54afb095d8ea/JOMFP-25-517-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/643882759961/JOMFP-25-517-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/e8d754d17354/JOMFP-25-517-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d6b/8859597/ad8bf8e57917/JOMFP-25-517-g006.jpg

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Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Tumors of the Salivary Gland.世界卫生组织头颈部肿瘤分类第4版更新:涎腺肿瘤
Head Neck Pathol. 2017 Mar;11(1):55-67. doi: 10.1007/s12105-017-0795-0. Epub 2017 Feb 28.
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Polymorphous Low-Grade Adenocarcinoma of the Palate: A Rare Case Report.腭部多形性低度恶性腺癌:1例罕见病例报告
Iran J Cancer Prev. 2015 Feb 13;9(1):e3447. doi: 10.17795/ijcp-3447. eCollection 2016 Feb.
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Histopathological spectrum of polymorphous low-grade adenocarcinoma.
多形性低度恶性腺癌的组织病理学谱
J Oral Maxillofac Pathol. 2015 May-Aug;19(2):266. doi: 10.4103/0973-029X.164555.
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Polymorphous low grade adenocarcinoma.多形性低度恶性腺癌
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