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疫情期间的过敏与免疫疗法

Allergy and Immunotherapy During the Pandemic.

作者信息

Davis Elizabeth Mahoney

机构信息

Department of Otolaryngology-Head and Neck Surgery, Boston University School of Medicine, 830 Harrison Avenue, Suite 1400, Boston, MA 02118 USA.

出版信息

Curr Otorhinolaryngol Rep. 2022;10(2):167-171. doi: 10.1007/s40136-022-00393-7. Epub 2022 Mar 9.

DOI:10.1007/s40136-022-00393-7
PMID:35281222
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8905013/
Abstract

PURPOSE OF REVIEW

To summarize and review recent literature on the role of allergen immunotherapy in the setting of a worldwide pandemic.

RECENT FINDINGS

At the start of the SARS-CoV-2 pandemic, most elective ambulatory patient care services, including allergen immunotherapy, were suspended. Now with medical practices reopening, allergists must establish plans and protocols for resuming care of allergy patients, including strategies for restarting allergen immunotherapy. While there are no published evidence-based protocols for resuming allergen immunotherapy, limited scientific data and expert opinion suggest that the major factor in dose adjustment is the time elapsed from the last dose.

SUMMARY

Resuming outpatient allergy services in the setting of the COVID-19 pandemic poses many challenges to the practitioner. Allergy specialists are now faced with developing prudent and evidence-based strategies for safely resuming allergen immunotherapy, while also maintaining a safe environment for staff and patients.

摘要

综述目的

总结并回顾近期关于变应原免疫疗法在全球大流行背景下作用的文献。

最新发现

在严重急性呼吸综合征冠状病毒2(SARS-CoV-2)大流行开始时,包括变应原免疫疗法在内的大多数非紧急门诊患者护理服务都暂停了。现在随着医疗业务重新开放,过敏症专科医生必须制定恢复过敏患者护理的计划和方案,包括重新启动变应原免疫疗法的策略。虽然目前尚无已发表的基于证据的恢复变应原免疫疗法的方案,但有限的科学数据和专家意见表明,剂量调整的主要因素是距上次给药的时间。

总结

在2019冠状病毒病(COVID-19)大流行背景下恢复门诊过敏服务给从业者带来了诸多挑战。过敏症专科医生现在面临着制定谨慎且基于证据的策略以安全恢复变应原免疫疗法,同时还要为工作人员和患者维持一个安全的环境。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f9e/8905013/f189112461d1/40136_2022_393_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f9e/8905013/f189112461d1/40136_2022_393_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f9e/8905013/f189112461d1/40136_2022_393_Fig1_HTML.jpg

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本文引用的文献

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COVID-19 and allergy: How to take care of allergic patients during a pandemic?COVID-19 与过敏:大流行期间如何照顾过敏患者?
Pediatr Allergy Immunol. 2020 Nov;31 Suppl 26(Suppl 26):96-101. doi: 10.1111/pai.13367.
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COVID-19 pandemic: Practical considerations on the organization of an allergy clinic-An EAACI/ARIA Position Paper.COVID-19 大流行:关于组织过敏诊所的实用注意事项——一项 EAACI/ARIA 立场文件。
Allergy. 2021 Mar;76(3):648-676. doi: 10.1111/all.14453.
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Allergen Immunotherapy in the Era of SARS-CoV-2.新冠病毒时代的变应原免疫疗法
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Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis.变应原免疫疗法治疗变应性哮喘:系统评价和荟萃分析。
Allergy. 2017 Dec;72(12):1825-1848. doi: 10.1111/all.13208. Epub 2017 Jul 6.
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Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis.变应性鼻炎结膜炎的变应原免疫治疗:系统评价和荟萃分析。
Allergy. 2017 Nov;72(11):1597-1631. doi: 10.1111/all.13201. Epub 2017 Jul 14.
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Survey on immunotherapy practice patterns: dose, dose adjustments, and duration.免疫疗法实践模式调查:剂量、剂量调整和持续时间。
Ann Allergy Asthma Immunol. 2012 May;108(5):373-378.e3. doi: 10.1016/j.anai.2012.03.009.