Chen Shi-Qi, Ge Li-Juan, Chen Guo-Qing, He Wen-Juan, Guo Juan-Juan, Li Yan, Shi Lin, Cheng Yan-Li
Department of Pediatrics, the General Hospital of Ningxia Medical University, Yinchuan, China.
Department of Radiology, the General Hospital of Ningxia Medical University, Yinchuan, China.
Transl Pediatr. 2022 Feb;11(2):204-211. doi: 10.21037/tp-21-601.
It is reported that the incidence of language development disorder in children at the age of 2 is as high as 17.0%. Timely discovery of the high-risk factors of language development disorder in children and early intervention can greatly reduce the incidence of language development disorder and shorten the course and condition of the patients with language development disorder. Therefore, in order to facilitate prompt diagnosis and early interventions for children with language development disorder (DLD) and improve their language ability, this study explored the influence of perinatal factors on the language development of children in Ningxia and identified the unfavorable and favorable factors that influenced language development.
Children diagnosed in the General Hospital of Ningxia Medical University during 2018-2021 who met the screening criteria for DLD and practical pediatric diagnostic criteria for DLD were enrolled in this study. Perinatal factors (gestational age, weight, sex, delivery mode, maternal age, presence of intrauterine infection, asphyxia) were retrospectively analyzed. The perinatal factors affecting language development were assessed using a one-way analysis of variance (ANOVA).
Among 1,500 children aged 0-3, 240 cases (16.00%) had language delay. Of these, 122 were male and 118 were female. There were 115 cases of comprehension and expression disorder, 30 cases of articulation disorder, and 90 cases of mixed manifestation. And there were 194 cases with definite intrauterine and perinatal high-risk factors or neonatal diseases, accounting for 80.83% of the total number of children with language delay.
In Ningxia, factors in the neonatal period are the main cause of DLD, followed by fetal and maternal factors. Ischemic encephalopathy is the most common factor.
据报道,2岁儿童语言发育障碍的发生率高达17.0%。及时发现儿童语言发育障碍的高危因素并进行早期干预,可大大降低语言发育障碍的发生率,缩短语言发育障碍患者的病程和病情。因此,为了便于对语言发育障碍(DLD)儿童进行及时诊断和早期干预,提高其语言能力,本研究探讨了围产期因素对宁夏儿童语言发育的影响,并确定了影响语言发育的不利和有利因素。
本研究纳入了2018年至2021年期间在宁夏医科大学总医院确诊且符合DLD筛查标准及实用儿科DLD诊断标准的儿童。对围产期因素(胎龄、体重、性别、分娩方式、母亲年龄、宫内感染情况、窒息情况)进行回顾性分析。采用单因素方差分析(ANOVA)评估影响语言发育的围产期因素。
在1500名0至3岁的儿童中,有240例(16.00%)存在语言发育迟缓。其中,男性122例,女性118例。有115例存在理解和表达障碍,30例存在构音障碍,90例为混合表现。有194例存在明确的宫内和围产期高危因素或新生儿疾病,占语言发育迟缓儿童总数的80.83%。
在宁夏,新生儿期因素是DLD的主要原因,其次是胎儿和母亲因素。缺血性脑病是最常见的因素。