Lee Christopher, Copp Jonathan
Department of Orthopaedic Surgery, University of California Los Angeles, Los Angeles.
Department of Orthopaedic Surgery, University of California Davis, Davis, California.
OTA Int. 2022 Mar 10;5(1 Suppl):e161. doi: 10.1097/OI9.0000000000000161. eCollection 2022 Mar.
Fracture healing remains a complex process routinely evaluated in clinical practice with sequential radiographs. Assessing the presence of union is a critical issue in patient care, with widespread implications in terms of overall decision-making and postoperative rehabilitation. Nonunion assessment, whether it be with radiographs or more advanced imaging, has far-reaching consequences for the patient in addition to the health care system. The purpose of this review was to explore new, emerging modalities for the assessment of fracture healing.
A review of the current, relevant literature regarding the use of serologic markers and radiostereometric analysis was conducted, and the results were summarized.
Emerging techniques to assess fracture healing have been evaluated, including the use of serologic markers as well as radiostereometric analysis. Their potential applications extend beyond the simple assessment of a united fracture, with the capacity to predict nonunion at earlier phases of care.
While early results appear promising, the current application of serologic markers and radiostereometric analysis as a means to assess fracture healing remains limited, and future larger-scale studies are needed to establish concrete and tailored guidelines for use.
骨折愈合仍是一个复杂的过程，在临床实践中通常通过系列X线片进行评估。评估骨折愈合情况是患者护理中的关键问题，对整体决策和术后康复有着广泛影响。无论使用X线片还是更先进的成像技术来评估骨不连，除了对医疗系统外，对患者也会产生深远影响。本综述的目的是探索评估骨折愈合的新出现的方法。
对当前有关血清学标志物和放射立体测量分析应用的相关文献进行综述，并总结结果。
已对评估骨折愈合的新兴技术进行了评估，包括血清学标志物的应用以及放射立体测量分析。它们的潜在应用不仅限于简单评估骨折愈合，还能够在护理的早期阶段预测骨不连。
虽然早期结果看起来很有前景，但目前血清学标志物和放射立体测量分析作为评估骨折愈合手段的应用仍然有限，需要未来进行更大规模的研究，以建立具体且适用的使用指南。
