Al-Jahdhami Issa, Al-Mawali Adhra, Bennji Sami M
Department of Medicine, Armed Forced Hospital, Muscat, Oman.
Centre of Studies and Research, Ministry of Health, Muscat, Oman.
Oman Med J. 2022 Jan 31;37(1):e343. doi: 10.5001/omj.2022.52. eCollection 2022 Jan.
COVID-19 pandemic has been associated with high short-term morbidity and mortality. Lungs are the main organs affected by SARS-CoV-2 infection. In the long-term, the pulmonary sequelae related to COVID-19 are expected to rise significantly leading to an extended impact on community health and health care facilities. A wide variety of long-term respiratory complications secondary to COVID-19 have been described ranging from persistent symptoms and radiologically observable changes to impaired respiratory physiology, vascular complications, and pulmonary fibrosis. Even after two-years, respiratory sequalae related to post-acute SARS-CoV-2 infection have not been fully explored and understood. The main treatment for most COVID-19 respiratory complications is still symptomatic and supportive-care oriented. In this review article, we shed light on current knowledge of the post-COVID-19 complications, focusing on pulmonary fibrosis, treatment directions, and recommendations to physicians.
新冠疫情与高短期发病率和死亡率相关。肺部是受新冠病毒2感染影响的主要器官。从长远来看，与新冠相关的肺部后遗症预计将大幅增加，从而对社区健康和医疗设施产生更大影响。已经描述了新冠引发的多种长期呼吸并发症，从持续症状、影像学可观察到的变化到呼吸生理受损、血管并发症和肺纤维化。即使在两年后，与急性新冠病毒2感染后相关的呼吸后遗症仍未得到充分研究和了解。大多数新冠呼吸并发症的主要治疗方法仍然是以对症和支持治疗为主。在这篇综述文章中，我们阐明了关于新冠后并发症的现有知识，重点关注肺纤维化、治疗方向以及给医生的建议。
