Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Inonu University Faculty of Medicine, Malatya, Turkey.
Acta Clin Croat. 2022 Feb;60(3):347-353. doi: 10.20471/acc.2021.60.03.02.
The objective was to investigate whether the method of treatment (surgical or medical) affects achieving a new pregnancy, as well as the time to and prognosis of the new pregnancy, in women with ectopic pregnancy (EP). Information on patients treated in our hospital between 2013 and 2014 for EP was retrieved from the computerized patient records. Data on whether these patients achieved pregnancy after EP treatment, time from treatment to new pregnancy, and prognosis of pregnancy were collected by phone interviews. A total of 101 women were analyzed. In addition to descriptive analysis, the χ-test and Kruskal Wallis test were used to compare the groups. A new pregnancy was present in 84 (83.2%) of the women after EP treatment. There was no significant difference among the women having undergone medical treatment (methotrexate), surgical treatment, medical treatment followed by surgical treatment, or observational management approach in terms of achieving a new pregnancy after treatment and time to and prognosis of the new pregnancy. The study could not determine which treatment method would be superior in women with EP and in planning future pregnancy, but concluded that close clinical and laboratory monitoring is appropriate before deciding on aggressive interventions.
目的在于探究异位妊娠（EP）患者的治疗方法（手术或药物）是否会影响其妊娠的获得，以及妊娠的时间和预后。从计算机化的患者记录中检索了 2013 年至 2014 年在我院接受治疗的 EP 患者的信息。通过电话访谈收集了这些患者在 EP 治疗后是否怀孕、从治疗到新妊娠的时间以及妊娠预后的数据。共分析了 101 名女性。除了描述性分析外，还使用 χ 检验和 Kruskal Wallis 检验比较了各组之间的差异。101 名女性中有 84 名（83.2%）在 EP 治疗后成功怀孕。在接受药物治疗（甲氨蝶呤）、手术治疗、药物治疗后手术治疗或观察管理方法的女性中，治疗后获得新妊娠的情况以及新妊娠的时间和预后没有显著差异。本研究无法确定哪种治疗方法对 EP 患者及其未来妊娠计划更为优越，但得出的结论是，在决定采取积极干预措施之前，进行密切的临床和实验室监测是合适的。
