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坦桑尼亚北部 HIV 感染者中高血压、糖尿病和肥胖的流行情况及其预测因素。

Prevalence and predictors of uncontrolled hypertension, diabetes, and obesity among adults with HIV in northern Tanzania.

机构信息

Department of Surgery, Duke University School of Medicine, Durham, NC, USA.

Duke Global Health Institute, Durham, NC, USA.

出版信息

Glob Public Health. 2022 Dec;17(12):3747-3759. doi: 10.1080/17441692.2022.2049344. Epub 2022 Mar 13.

DOI:10.1080/17441692.2022.2049344
PMID:35282776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9468185/
Abstract

HIV is associated with increased risk of cardiovascular disease, but there has been less study of cardiovascular comorbidities among people with HIV in sub-Saharan Africa. In a cross-sectional observational study, Tanzanian adults presenting for outpatient HIV care completed a questionnaire and underwent weight, height, blood pressure, and blood glucose measurement. Hypertension was defined by blood pressure ≥140/90 mmHg or self-reported hypertension. Uncontrolled hypertension was defined as measured blood pressure ≥140/90 mmHg. Diabetes was defined by fasting glucose ≥126 mg/dl, random glucose ≥200 mg/dl, or self-reported diabetes. Obesity was defined by body mass index ≥30 kg/m. Multivariate logistic regression was performed to identify predictors of uncontrolled hypertension. Among 500 participants, 173 (34.6%) had hypertension, 21 (4.2%) had diabetes, and 99 (19.8%) were obese. Of those with hypertension, 116 (67.1%) were unaware of their hypertension, and 155 (89.6%) had uncontrolled hypertension. In multivariate analysis, uncontrolled hypertension was associated with older age (OR 1.07, 95% CI: 1.05-1.10, < 0.001) and higher body mass index (OR 1.17, 95% CI: 1.11-1.22, < 0.001). Interventions are needed to improve screening and treatment for hypertension, diabetes, and obesity among Tanzanians with HIV.

摘要

HIV 与心血管疾病风险增加相关,但在撒哈拉以南非洲的 HIV 感染者中,对心血管合并症的研究较少。在一项横断面观察性研究中,坦桑尼亚成年人为门诊 HIV 护理就诊,完成了一份问卷,并进行了体重、身高、血压和血糖测量。高血压的定义为血压≥140/90mmHg 或自我报告的高血压。未控制的高血压定义为测量的血压≥140/90mmHg。糖尿病的定义为空腹血糖≥126mg/dl、随机血糖≥200mg/dl 或自我报告的糖尿病。肥胖的定义为身体质量指数≥30kg/m。进行多变量逻辑回归以确定未控制的高血压的预测因素。在 500 名参与者中,173 名(34.6%)患有高血压,21 名(4.2%)患有糖尿病,99 名(19.8%)肥胖。在患有高血压的患者中,有 116 名(67.1%)不知道自己患有高血压,有 155 名(89.6%)患有未控制的高血压。在多变量分析中,未控制的高血压与年龄较大(OR 1.07,95%CI:1.05-1.10,<0.001)和较高的体重指数(OR 1.17,95%CI:1.11-1.22,<0.001)相关。需要采取干预措施,以改善坦桑尼亚 HIV 感染者中高血压、糖尿病和肥胖的筛查和治疗。

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