Division of Infectious Diseases and Global Medicine, University of Florida, Gainesville FL, USA.
Division of Infectious Diseases, Duke University, Durham, NC, USA.
Pan Afr Med J. 2022 Apr 7;41:285. doi: 10.11604/pamj.2022.41.285.26952. eCollection 2022.
Preeti Manavalan et al. Hypertension among adults enrolled in HIV care in northern Tanzania: comorbidities, cardiovascular risk, and knowledge, attitudes and practices. Pan African Medical Journal. 2022;41(285). 10.11604/pamj.2022.41.285.26952.
the epidemiology of non-communicable diseases (NCDs) among people living with HIV (PLHIV) in sub-Saharan Africa is poorly described. In this observational study we examined a cohort of hypertensive PLHIV in northern Tanzania and described comorbidities, cardiovascular risk, and hypertension knowledge, attitudes and practices.
consecutive patients attending an HIV clinic were screened for hypertension; those who met hypertension study criteria were enrolled. Participants completed a hypertension knowledge, attitudes and practices survey, and underwent height, weight, and waist circumference measurements and urine dipstick, fasting blood sugar, and lipid panel analyses. Kidney disease was defined as 1+ proteinuria, diabetes mellitus was defined as fasting glucose >126mg/dL, and 10-year atherosclerotic cardiovascular disease (ASCVD) risk was defined per the Pooled Cohorts Equations.
of 555 screened patients, 105 met hypertension criteria and 91 (86.7%) were enrolled. The prevalence of diabetes mellitus, kidney disease, and overweight or obesity was 8.8%, 28.6%, and 86.7%, respectively. Almost all participants (n=86, 94.5%) had two or more medical comorbidities. More than half (n=39, 52.7%) had intermediate or high 10-year risk for an ASCVD event. While only 3 (3.3%) participants were able to define hypertension correctly, most would seek care at a medical facility (n=89, 97.8%) and take medication chronically for hypertension (n=79, 87.8%).
we found a high burden of medical comorbidity and ASCVD risk among hypertensive PLHIV in northern Tanzania. Integration of routine NCD screening in the HIV clinical setting, in combination with large-scale educational campaigns, has the potential to impact clinical outcomes in this high-risk population.
Preeti Manavalan 等人。坦桑尼亚北部接受艾滋病毒护理的成年人中的高血压：合并症、心血管风险以及知识、态度和实践。非洲泛医学杂志。2022;41(285).10.11604/pamj.2022.41.285.26952.
撒哈拉以南非洲地区艾滋病毒感染者（PLHIV）中非传染性疾病（NCD）的流行病学情况描述甚少。在这项观察性研究中，我们研究了坦桑尼亚北部高血压 PLHIV 的队列，并描述了合并症、心血管风险以及高血压知识、态度和实践。
连续筛查参加艾滋病毒诊所的患者，对符合高血压研究标准的患者进行入组。参与者完成了高血压知识、态度和实践调查，并进行了身高、体重和腰围测量以及尿液试纸、空腹血糖和血脂分析。肾病定义为 1+蛋白尿，糖尿病定义为空腹血糖>126mg/dL，10 年动脉粥样硬化性心血管疾病（ASCVD）风险定义为基于合并队列方程。
在 555 名筛查患者中，有 105 名符合高血压标准，其中 91 名（86.7%）入组。糖尿病、肾病和超重或肥胖的患病率分别为 8.8%、28.6%和 86.7%。几乎所有参与者（n=86，94.5%）都有两种或两种以上的合并症。超过一半（n=39，52.7%）有中等或高 ASCVD 事件 10 年风险。尽管只有 3 名（3.3%）参与者能够正确定义高血压，但大多数人会到医疗机构就诊（n=89，97.8%）并长期服用降压药（n=79，87.8%）。
我们发现坦桑尼亚北部高血压 PLHIV 中存在很高的合并症和 ASCVD 风险负担。在艾滋病毒临床环境中常规进行非传染性疾病筛查，并结合大规模教育运动，有可能影响这一高危人群的临床结果。
