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中国浙江省黄曲霉毒素的发生与暴露评估。

Occurrence and exposure assessment of aflatoxins in Zhejiang province, China.

机构信息

Department of Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China.

School of Medicine, Ningbo University, Ningbo, China.

出版信息

Environ Toxicol Pharmacol. 2022 May;92:103847. doi: 10.1016/j.etap.2022.103847. Epub 2022 Mar 11.

Abstract

The purpose of this study was to assess the risk of aflatoxins due to multiple food consumption among the Zhejiang population. Ultra-high-performance liquid chromatography coupled with tandem mass spectrometry method was used to determine aflatoxins in 792 samples. Aflatoxins were detected in 27.1% of the samples at levels between 0.07 and 262.63 μg kg, and aflatoxins B was the most frequently detected among different types of samples. 0.8% of peanut oil, 3.39% of nut products as well as 1.1% of condiments contaminated with aflatoxins B exceeded China national tolerance limits. Peanut oil had the highest incidence of aflatoxin, with a range from 0.17 to 22.50 μg kg. Using bags conferred limited advantages in reducing aflatoxin contents. Moreover, peanut and rice were the main contributors to dietary exposure to aflatoxins among Zhejiang residents. Finally, the margin of exposure values obtained by rice consumption were far from the safe margin of 10,000, indicating a potential risk to public health. The results pointed out the need for further prioritization of aflatoxins B risk-management actions in Zhejiang.

摘要

本研究旨在评估浙江人群因多种食物消费而摄入黄曲霉毒素的风险。采用超高效液相色谱-串联质谱法对 792 份样品进行了黄曲霉毒素检测。结果显示,27.1%的样品中检出黄曲霉毒素,浓度在 0.07 至 262.63μg/kg 之间,不同类型的样品中以黄曲霉毒素 B 检出率最高。花生油、坚果制品和调味品中分别有 0.8%、3.39%和 1.1%的样品中黄曲霉毒素 B 超过中国国家耐受限量。花生油的黄曲霉毒素检出率最高,范围为 0.17 至 22.50μg/kg。使用塑料袋在降低黄曲霉毒素含量方面的效果有限。此外,花生和大米是浙江居民膳食摄入黄曲霉毒素的主要来源。最后,通过大米消费获得的暴露量值远远低于 10000 的安全边际,表明对公众健康存在潜在风险。研究结果表明,有必要在浙江进一步优先考虑黄曲霉毒素 B 的风险管理措施。

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