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睡眠良好自闭症谱系障碍(ASD):一项针对小学年龄段自闭症儿童进行简短行为睡眠干预的随机对照试验。

Sleeping Sound Autism Spectrum Disorder (ASD): a randomised controlled trial of a brief behavioural sleep intervention in primary school-aged autistic children.

作者信息

Papadopoulos Nicole, Sciberras Emma, Hiscock Harriet, Williams Katrina, McGillivray Jane, Mihalopoulos Cathrine, Engel Lidia, Fuller-Tyszkiewicz Matthew, Bellows Susannah T, Marks Deborah, Howlin Patricia, Rinehart Nicole

机构信息

Deakin Child Study Centre, Deakin University, Burwood, VIC, Australia.

School of Educational Psychology and Counselling, Faculty of Education, Monash University, Clayton, VIC, Australia.

出版信息

J Child Psychol Psychiatry. 2022 Nov;63(11):1423-1433. doi: 10.1111/jcpp.13590. Epub 2022 Mar 13.

Abstract

BACKGROUND

Behavioural sleep problems are common in children with autism spectrum disorder (ASD); however, evidence for the efficacy of behavioural sleep interventions is limited. This study examined the efficacy of a brief behavioural sleep intervention in autistic children. It was hypothesised that the intervention would reduce overall child sleep problems (primary outcome), in addition to improvements in children's social, emotional, cognitive, academic functioning, and quality of life, and parent/caregivers' stress, quality of life, and mental health (secondary outcomes).

METHODS

A randomised controlled trial was conducted with participants randomised via a computer-generated sequence to the sleeping sound intervention (n = 123) or treatment as usual (n = 122) group. Participants comprised 245 children with an ASD diagnosis. Inclusion criteria were as follows: confirmation of DSM IV or DSM-5 diagnosis of ASD, participants aged between 5 and 13 years and parent/caregiver report of moderate-severe sleep problems. Exclusion criteria were as follows: parent/caregiver intellectual disability or lacking sufficient English to complete questionnaires; and child participant with co-occurring medical conditions known to impact sleep. The intervention group received the sleeping sound intervention (2 × 50-min face-to-face sessions plus follow-up phone call) by a trained clinician.

RESULTS

Change in children's sleep problems was measured by the Children's Sleep Habits Questionnaire (CSHQ) at 3 months post randomisation. Parents/caregivers of children in the intervention group reported a reduction in child sleep problems at 3 months post randomisation (effect size: E.S -0.7). There were also small effects in a number of child (internalising symptoms, emotional behavioural disturbance and quality of life) and parent/caregiver (mental health, parenting stress and quality of life) outcomes; however, these did not remain significant when controlling for multiple comparisons.

CONCLUSIONS

The sleeping sound ASD intervention is an efficacious and practical way to reduce sleep problems for autistic children. This brief behavioural intervention has the potential to be embedded easily into the Australian healthcare system.

摘要

背景

行为性睡眠问题在自闭症谱系障碍(ASD)儿童中很常见;然而,行为性睡眠干预疗效的证据有限。本研究考察了一种简短的行为性睡眠干预对自闭症儿童的疗效。研究假设该干预除了能改善儿童的社交、情感、认知、学业功能及生活质量,以及家长/照顾者的压力、生活质量和心理健康(次要结果)外,还能减少儿童总体睡眠问题(主要结果)。

方法

进行了一项随机对照试验,参与者通过计算机生成的序列随机分为睡眠声音干预组(n = 123)或常规治疗组(n = 122)。参与者包括245名被诊断为ASD的儿童。纳入标准如下:确诊为DSM-IV或DSM-5的ASD诊断,年龄在5至13岁之间的参与者,以及家长/照顾者报告有中度至重度睡眠问题。排除标准如下:家长/照顾者有智力障碍或英语水平不足以完成问卷;以及患有已知会影响睡眠的并发疾病的儿童参与者。干预组由一名经过培训的临床医生进行睡眠声音干预(2次×50分钟面对面课程加后续电话随访)。

结果

随机分组后3个月,通过儿童睡眠习惯问卷(CSHQ)测量儿童睡眠问题的变化。干预组儿童的家长/照顾者报告,随机分组后3个月儿童睡眠问题有所减少(效应量:E.S -0.7)。在一些儿童(内化症状、情绪行为障碍和生活质量)和家长/照顾者(心理健康、育儿压力和生活质量)结果方面也有小的效应;然而,在控制多重比较时,这些效应不再显著。

结论

睡眠声音ASD干预是减少自闭症儿童睡眠问题的一种有效且实用的方法。这种简短的行为干预有可能很容易地融入澳大利亚的医疗保健系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f887/9790415/71863b61b053/JCPP-63-1423-g001.jpg

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