Quigley M R, Bailes J E, Kwaan H C, Cerullo L J, Block S
J Vasc Surg. 1986 Sep;4(3):217-9. doi: 10.1067/mva.1986.avs0040217.
Use of the milliwatt CO2 laser to perform microvascular anastomoses is associated with characteristic histologic changes, including intimal hyperplasia and medial necrosis. The extent of myointimal proliferation after both suture and laser-assisted vascular anastomosis was assessed in the rat femoral artery model. At 2 weeks the average intimal height of the laser-anastomosed vessels was 11.7 +/- 2.2 microns (mean +/- standard error of the mean) vs. 21.3 +/- 3.2 microns for sutured arteries (p less than 0.05). By 6 weeks the groups were equivalent (laser, 25.6 +/- 4.6 microns; suture, 17.3 +/- 1.2 microns; p, not significant). The medial changes associated with the laser-assisted method appear to inhibit the proliferative response at 2 weeks but are reversed by 6 weeks.
使用毫瓦级二氧化碳激光进行微血管吻合与特征性组织学变化相关，包括内膜增生和中层坏死。在大鼠股动脉模型中评估了缝合和激光辅助血管吻合术后肌内膜增殖的程度。2周时，激光吻合血管的平均内膜高度为11.7±2.2微米（平均值±平均标准误差），而缝合动脉为21.3±3.2微米（p<0.05）。到6周时，两组相当（激光组，25.6±4.6微米；缝合组，17.3±1.2微米；p，无显著性差异）。与激光辅助方法相关的中层变化似乎在2周时抑制了增殖反应，但在6周时逆转。
