Department of Oral Pathology & Microbiology and Forensic Odontology. Laxmi bai institute of dental sciences and hospital, Patiala, Punjab, India.
Department of Oral and Maxillofacial surgery, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab, India.
Acta Medica (Hradec Kralove). 2021;64(4):227-231. doi: 10.14712/18059694.2022.7.
Coronavirus infectious disease-19 caused by Severe acute respiratory distress syndrome-coronavirus-2 has emerged to be an emergency global health crisis for more than a year. And, as the disease has spread, a number of new clinical features have been observed in these patients. Immunosuppression caused by this disease results in an exacerbation of pre-existing infections. While corticosteroids are considered a life-saving therapeutic intervention for this pandemic, they have proved to be a double-edged sword and their indiscriminate use has produced some deleterious results. Recently, in the backdrop of this expression, a notable rise in invasive fungal infections has been identified even in the post-remission phase. Mucormycosis, Aspergillosis, and Candidiasis are the three most common opportunistic fungal infections among those observed. COVID-19 patients with diabetes mellitus are already at a higher risk of developing such secondary infections due to impaired immunity. Here we present a rare case report of a 50-year old male diabetic mellitus patient diagnosed with dual fungal infections (Aspergillosis along with Mucormycosis) leading to maxillary sinusitis as a post-COVID manifestation. To our knowledge, this is the first such case reported till date.
由严重急性呼吸综合征冠状病毒 2 引起的新型冠状病毒传染病已持续超过一年，成为全球紧急卫生危机。随着疾病的传播，在这些患者中观察到了许多新的临床特征。这种疾病引起的免疫抑制会导致先前存在的感染恶化。尽管皮质类固醇被认为是治疗这种大流行的救命疗法，但事实证明它们是一把双刃剑，其不加区分的使用产生了一些有害的后果。最近，在这种情况下，即使在缓解后阶段，也发现侵袭性真菌感染明显增加。毛霉菌病、曲霉病和念珠菌病是观察到的三种最常见的机会性真菌感染。由于免疫受损，患有糖尿病的 COVID-19 患者已经处于发生此类继发感染的更高风险中。在这里，我们报告了一例罕见的 50 岁男性糖尿病患者的病例，该患者被诊断出患有双重真菌感染（曲霉病合并毛霉菌病），导致上颌窦炎作为 COVID 后的表现。据我们所知，这是迄今为止首例此类病例报告。
