从哈萨克斯坦阿拉木图医院分离出的革兰氏阳性机会致病菌的全基因组序列
Complete Genome Sequences of Gram-Positive Opportunistic Pathogens Isolated from Hospitals in Almaty, Kazakhstan.
作者信息
Korotetskiy Ilya S, Jumagaziyeva Ardak B, Kerimzhanova Bahkytzhan, Reva Oleg N, Shilov Sergey V, Kuznetsova Tatyana, Ivanova Ludmila, Korotetskaya Nadezhda, Bekmukhamedova Aimana, Satylgankyzy Ganiya, Klivleyeva Nailya G
机构信息
Scientific Center for Anti-Infectious Drugs, Almaty, Kazakhstan.
Centre for Bioinformatics and Computational Biology, Department of Biochemistry, Genetics, and Microbiology, University of Pretoria, Pretoria, South Africa.
出版信息
Microbiol Resour Announc. 2022 Apr 21;11(4):e0009322. doi: 10.1128/mra.00093-22. Epub 2022 Mar 14.
Abstract
The appearance of drug-resistant pathogens reduces the therapeutic applicability of antibiotics and increases the rate of hospital infections among patients. Complete genome sequences of four Gram-positive clinical isolates of Streptococcus and Staphylococcus were obtained and analyzed to serve as model microorganisms for further studies on drug-induced antibiotic resistance reversion.
摘要
耐药病原体的出现降低了抗生素的治疗适用性，并增加了患者医院感染的发生率。获得并分析了四种革兰氏阳性临床分离株（链球菌和葡萄球菌）的完整基因组序列，以作为进一步研究药物诱导抗生素耐药性逆转的模式微生物。
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