Pietropaoli Francesca, Pantalone Sara, Cichelli Angelo, d'Alessandro Nicola
Department of Innovative Technology in Medicine and Dentistry, University "G. d'Annunzio", Chieti, Italy.
Department of Engineering and Geology, University "G. d'Annunzio", Chieti, Italy.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2022 May;39(5):853-887. doi: 10.1080/19440049.2022.2046292. Epub 2022 Mar 14.
Acrylamide (AA) is considered genotoxic, neurotoxic and a 'probable human carcinogen'. It is included in group 2 A of the International Agency for Research on Cancer (IARC). The formation of AA occurs when starch-based foods are subjected to temperatures higher than 120 °C in an atmosphere with very low water content. The aim of this review is to shed light on the toxicological aspects of AA, showing its regulatory evolution, and describing the most interesting mitigation techniques for each food category involved, with a focus on compliance with EU legislation in the various classes of consumer products of industrial origin in Europe.
丙烯酰胺(AA)被认为具有基因毒性、神经毒性,是一种“可能的人类致癌物”。它被列入国际癌症研究机构(IARC)的2A组。当淀粉类食品在水分含量极低的环境中经受高于120°C的温度时,就会形成AA。本综述的目的是阐明AA的毒理学方面,展示其监管演变,并描述所涉及的各类食品中最有趣的缓解技术,重点关注欧洲各类工业源消费品对欧盟法规的合规情况。