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一项关于标准化人参提取物对健康志愿者心理运动表现影响的双盲、安慰剂对照临床研究。

A double-blind, placebo-controlled clinical study on the effect of a standardized ginseng extract on psychomotor performance in healthy volunteers.

作者信息

D'Angelo L, Grimaldi R, Caravaggi M, Marcoli M, Perucca E, Lecchini S, Frigo G M, Crema A

出版信息

J Ethnopharmacol. 1986 Apr-May;16(1):15-22. doi: 10.1016/0378-8741(86)90063-2.

DOI:10.1016/0378-8741(86)90063-2
PMID:3528672
Abstract

Various tests of psychomotor performance were carried out in a group of 16 healthy male volunteers given a standardized preparation of Korean ginseng (G 115; 100 mg twice a day for 12 weeks) and in a similar group given identical placebo capsules under double-blind conditions. A favourable effect of G 115 relative to baseline performance was observed in attention (cancellation test), processing (mental arithmetic, logical deduction), integrated sensory-motor function (choice reaction time) and auditory reaction time. However, end performance of the G 115 group was superior statistically to the placebo group only in mental arithmetic. No difference between G 115 and placebo was found in tests of pure motor function (tapping test), recognition (digit symbol substitution) and visual reaction time. No adverse effects were reported. It is concluded that G 115 may be superior to placebo in improving certain psychomotor functions in healthy subjects.

摘要

对一组16名健康男性志愿者进行了各种心理运动表现测试。这些志愿者被给予标准化的高丽参制剂(G 115;每天两次,每次100毫克,共12周),另一组相似的志愿者在双盲条件下服用相同的安慰剂胶囊。在注意力(划消试验)、处理能力(心算、逻辑推理)、综合感觉运动功能(选择反应时间)和听觉反应时间方面,观察到G 115相对于基线表现有积极效果。然而,G 115组的最终表现仅在心算方面在统计学上优于安慰剂组。在纯运动功能测试(敲击试验)、识别(数字符号替换)和视觉反应时间方面,未发现G 115与安慰剂之间存在差异。未报告不良反应。结论是,G 115在改善健康受试者的某些心理运动功能方面可能优于安慰剂。

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