Battan V J, Planas-Girón G
Med Cutan Ibero Lat Am. 1986;14(2):120-4.
We present the case of a patient with the clinical and histopathological diagnosis of Reactive Perforating Collagenosis, the first case described in the Venezuelan Dermatological literature. The most frequent histopathological and differential clinical diagnoses are reviewed with regard to Kyrle's disease, Elastosis Perforans Serpiginosa and Perforating Folliculitis. Clinically our patient presented with a papular eruption over an erythematous base on the right forearm and the dorsum of the right hand. On the lower third on its ventral aspect these papules adopted a linear distribution suggesting an isomorphic reaction. Histopathologically, the phenomena of transepithelial elimination was observed. Finally we reviewed the multiple treatment modalities described in the literature for this disease. We treated our patient with topical retinoic acid at a 0.05% concentration nightly for seven nights with excellent results. At the present time she is free of cutaneous lesions.
我们报告一例临床及组织病理学诊断为反应性穿通性胶原病的患者，这是委内瑞拉皮肤病学文献中描述的首例病例。文中就 Kyrle 病、匐行性穿通性弹力纤维病和穿通性毛囊炎，对最常见的组织病理学及鉴别性临床诊断进行了综述。临床上，我们的患者右前臂和右手背出现了以红斑为基底的丘疹性皮疹。在右手腹侧下三分之一处，这些丘疹呈线状分布，提示同形反应。组织病理学检查发现了经上皮排除现象。最后，我们回顾了文献中描述的针对该疾病的多种治疗方式。我们用 0.05%浓度的外用维甲酸每晚给患者治疗七晚，效果极佳。目前她没有皮肤病变。
