Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya, Kuala Lumpur, Malaysia.
Pathog Glob Health. 2022 Sep;116(6):356-364. doi: 10.1080/20477724.2022.2035624. Epub 2022 Mar 14.
Information on the mosquito species that transmit canine filariosis is scanty. Hence, an experimental study was conducted to identify the potential vectors responsible for the transmission of Leidy and Buckley & Edeson. A total of 367 mosquitoes belonging to six species containing both laboratory and field strains (i.e. Theobald, Linnaeus, Skuse, Say, Theobald and Peyton & Harrison) were used in this study. All mosquitoes were artificially fed on either or i microfilariae (mfs) infected blood by using the Hemotek™ membrane feeding system. Out of 367 mosquitoes, 228 (64.9%) were fully engorged. After feeding on (20%) and (33%) mfs positive blood, the mortality rates for were found to be slightly lower than that of other species of mosquitoes. On the other hand, majority of were found to be incapable to withstand the infection of mfs as the mortality rates were relatively high ( = 71.4%; = 100.0%). was detected in and with infection rates of 50% and 25%, respectively. was the only species infected with with an infection rate of 69%. Our results showed that was an excellent experimental vector for both and . This study also documented the observation of , for the first time in the head region of s under a laboratory setting.
有关传播犬丝虫病的蚊子种类的信息很少。因此，进行了一项实验研究，以确定传播 Leidy 和 Buckley & Edeson 的潜在媒介。本研究共使用了 367 只蚊子，属于六个物种，包括实验室和野外菌株（即 Theobald、Linnaeus、Skuse、Say、Theobald 和 Peyton & Harrison）。所有蚊子均通过 Hemotek™膜饲养系统人工吸食或感染微丝蚴（mf）的血液。在 367 只蚊子中，有 228 只（64.9%）完全饱食。在吸食含有 20%（）和 33%（）mf 的阳性血液后，发现的死亡率略低于其他蚊子物种。另一方面，由于死亡率相对较高（=71.4%；=100.0%），大多数蚊子无法承受 mf 的感染。在和中检测到，感染率分别为 50%和 25%。是唯一一种感染的物种，感染率为 69%。我们的结果表明，是和的优良实验媒介。本研究还首次在实验室环境下观察到在头部区域感染。
