Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Higher Institution Centre of Excellence (HICoE), Tropical Infectious Diseases Research and Education Centre (TIDREC), University of Malaya, Kuala Lumpur, Malaysia.
Trop Biomed. 2021 Mar 1;38(1):145-149. doi: 10.47665/tb.38.1.025.
Canine vector-borne diseases (CVBDs) are increasingly becoming a cause for global concern because of their high morbidity and mortality rates in dogs. However, information on their occurrence in Malaysia is still scanty. In this study, a total of 103 dog blood samples were collected from two animal shelters in central Peninsular Malaysia and tested for the antibodies against Ehrlichia spp., Anaplasma spp., Borrelia burgdorferi, and the antigen of Dirofilaria immitis. Of the 103 tested dogs, 44.7% (46) were found to be seropositive for Ehrlichia spp., 30.1% (31) for Anaplasma spp. and 13.6% (14) for D. immitis. Co-infections of Anaplasma spp. + Ehrlichia spp. (18.5%, 19) were most prevalent, followed by Anaplasma spp. + D. immitis (1.9%; two) and D. immitis + Ehrlichia spp. (1.0%; one). Furthermore, three dogs (2.9%) were also found to have triple infection, testing seropositive for Ehrlichia spp., Anaplasma spp. and D. immitis. The dogs which were found to be seropositive with at least one pathogen were 66.7% (32/51) at shelter A, and 55.8% (29/52) at shelter B. Serological evidence showed that the exposure of major vector-borne diseases in dogs in shelters was relatively high in the surveyed areas. Routine detection and control of vector-borne diseases are of paramount importance for reducing the risk of CVBDs transmission in dogs and humans.
犬媒介传染病（CVBDs）因其在犬中的高发病率和死亡率而日益引起全球关注。然而，马来西亚有关此类疾病发生的信息仍然很少。在这项研究中，从马来西亚半岛中部的两个动物收容所采集了总共 103 份犬血样，并对埃立克体属、无形体属、伯氏疏螺旋体和犬恶丝虫抗原的抗体进行了检测。在 103 只受检犬中，有 44.7%（46 只）被检测出埃立克体属抗体呈阳性，30.1%（31 只）为无形体属抗体阳性，13.6%（14 只）为犬恶丝虫抗原阳性。最常见的是无形体属+埃立克体属混合感染（18.5%，19 只），其次是无形体属+犬恶丝虫（1.9%；2 只）和犬恶丝虫+埃立克体属（1.0%；1 只）。此外，还发现有 3 只（2.9%）犬同时感染了三种病原体，埃立克体属、无形体属和犬恶丝虫的抗体检测均呈阳性。在收容所 A 发现至少有一种病原体呈血清阳性的犬有 66.7%（32/51），在收容所 B 有 55.8%（29/52）。血清学证据表明，在所调查地区，收容所中犬主要媒介传染病的暴露率相对较高。常规检测和控制媒介传染病对于降低犬和人类 CVBDs 传播的风险至关重要。
