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子痫前期合并系统性红斑狼疮患者狼疮性腹膜炎致大量腹水:病例报告。

Massive ascites due to lupus peritonitis in a patient with pre-eclampsia and systemic lupus erythematosus: a case report.

机构信息

Department of Obstetrics and Gynecology, Niigata University Medical and Dental Hospital, 1-754 Asahimachi-dori, Chuo-ku, Niigata, 951-8520, Japan.

Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

出版信息

BMC Pregnancy Childbirth. 2022 Mar 14;22(1):203. doi: 10.1186/s12884-022-04550-0.

Abstract

BACKGROUND

Patients with systemic lupus erythematosus (SLE) are associated with pre-eclampsia. Pre-eclampsia can have systemic manifestations, such as ascites. Lupus peritonitis, a rare condition in patients with SLE, can also cause ascites.

CASE PRESENTATION

A 31-year-old woman, primigravida, with SLE had a blood pressure of 170/110 mmHg and proteinuria at 29 weeks of gestation. She was diagnosed with pre-eclampsia. Her blood pressure was stabilized by an antihypertensive drug. At 30 weeks of gestation, a cesarean section was performed for maternal safety because of decreased urine output and massive ascites. Postoperatively, re-accumulation of ascites was observed. On the fourth postoperative day, ascites (approximately 3 L) was discharged from the cesarean section wound. A decrease in serum complement concentrations was observed, and she was diagnosed as having lupus peritonitis. The steroid dose was increased and she recovered well thereafter.

CONCLUSIONS

Ascites occurs in pre-eclampsia and SLE, but determining which of these conditions causes ascites can be difficult. However, careful observation is necessary because of the differences in treatment of these two conditions.

摘要

背景

系统性红斑狼疮 (SLE) 患者与子痫前期有关。子痫前期可出现全身表现,如腹水。狼疮性腹膜炎是 SLE 患者的一种罕见情况,也可引起腹水。

病例介绍

一名 31 岁的初产妇,患有 SLE,在妊娠 29 周时血压为 170/110mmHg,且蛋白尿。她被诊断为子痫前期。她的血压通过降压药物得到稳定。由于尿量减少和大量腹水,为了母亲安全,在妊娠 30 周时进行了剖宫产术。术后,观察到腹水再次积聚。术后第 4 天,从剖宫产切口排出腹水(约 3L)。观察到血清补体浓度下降,诊断为狼疮性腹膜炎。增加了类固醇剂量,此后她恢复良好。

结论

腹水发生在子痫前期和 SLE 中,但确定哪种情况导致腹水可能具有难度。然而,由于这两种情况的治疗方法存在差异,因此需要仔细观察。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbad/8919585/077a4ddde208/12884_2022_4550_Fig1_HTML.jpg

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