副溶血性弧菌中质粒介导的抗生素耐药机制
Mechanisms of plasmid-mediated antibiotic resistances in Vibrio parahaemolyticus.
作者信息
Hasegawa H, Hamashima H, Arai T
出版信息
Microbiol Immunol. 1986;30(5):437-44. doi: 10.1111/j.1348-0421.1986.tb02969.x.
Abstract
The mechanisms of drug resistance of clinical isolate, Vibrio (V.) parahaemolyticus ST550, resistant to chloramphenicol (CP), aminoglycoside antibiotics (AGs) and beta-lactam antibiotics were investigated. The mechanisms of resistance to CP, AGs and beta-lactam antibiotics were dependent on chloramphenicol acetyltransferase (CAT), aminoglycoside-3"-adenylyltransferase AAD(3") and aminoglycoside-3'-phosphotransferase APH(3') and TEM type penicillinase, respectively.
摘要
对临床分离的副溶血性弧菌ST550菌株对氯霉素（CP）、氨基糖苷类抗生素（AGs）和β-内酰胺类抗生素的耐药机制进行了研究。对CP、AGs和β-内酰胺类抗生素的耐药机制分别依赖于氯霉素乙酰转移酶（CAT）、氨基糖苷-3''-腺苷酰转移酶AAD(3'')、氨基糖苷-3'-磷酸转移酶APH(3')和TEM型青霉素酶。
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