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肺部小细胞癌的岩骨转移。

Petrous metastasis of a lung small cell carcinoma.

出版信息

Tunis Med. 2021;99(11):1097-1100.

PMID:35288914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9390124/
Abstract

Malignant tumors of the temporal bone are rare. They include a wide histological variety. They are mostly primary tumors with an estimated incidence of 0.8-1.0 per 1,000,000 inhabitants per year [1]. Metastases form an uncommon subgroup. The clinical features of these temporal bone metastases are nonspecific and predominantly consist of hearing loss, vertigo, facial palsy, tinnitus, headache, otalgia or otorrhoea [2]. The aim of our publication is to report a rare case of metastasis in the temporal bone as initial manifestation of lung cancer. Our patient was a 44-year-old man who presented for a right mastoid swelling with a grade VI right facial nerve palsy. Imaging and biopsy confirmed the diagnosis of small cell lung carcinoma petrous metastasis. The treatment was palliative. An osteolytic lesion of the temporal bone in an elderly patient may fit with a primary tumor of the temporal bone. It must, also, suggest the diagnosis of metastasis. The malignant tumor most frequently responsible is breast cancer, but lung cancer must also be considered in smoking patients.

摘要

颞骨恶性肿瘤较为罕见。其包含广泛的组织学类型。这些肿瘤主要为原发性肿瘤,估计每年每 100 万人中有 0.8-1.0 例[1]。转移瘤为一不常见的亚组。这些颞骨转移瘤的临床特征无特异性,主要表现为听力损失、眩晕、面瘫、耳鸣、头痛、耳痛或耳漏[2]。我们发表的目的是报告一例肺癌首发表现为颞骨转移的罕见病例。我们的患者是一名 44 岁男性,因右侧乳突肿胀伴 VI 级右侧面神经麻痹就诊。影像学和活检证实为小细胞肺癌岩骨转移。治疗为姑息性的。老年患者颞骨溶骨性病变可能符合颞骨原发性肿瘤。此外,还应提示转移瘤的诊断。最常引起恶性肿瘤的是乳腺癌,但在吸烟患者中还必须考虑肺癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/face/9390124/a8e46138da61/image3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/face/9390124/5d91ba7d6ec1/image1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/face/9390124/a9771b1f4348/image2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/face/9390124/a8e46138da61/image3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/face/9390124/5d91ba7d6ec1/image1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/face/9390124/a9771b1f4348/image2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/face/9390124/a8e46138da61/image3.jpg

相似文献

1
Petrous metastasis of a lung small cell carcinoma.肺部小细胞癌的岩骨转移。
Tunis Med. 2021;99(11):1097-1100.
2
Metastatic Disease of the Temporal Bone: A Contemporary Review.颞骨转移性疾病:当代综述。
Laryngoscope. 2021 May;131(5):1101-1109. doi: 10.1002/lary.29096. Epub 2020 Sep 17.
3
Two cases of temporal bone metastases as presenting sign of lung cancer.两例以颞骨转移为首发表现的肺癌病例。
Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Feb;129(1):54-7. doi: 10.1016/j.anorl.2011.07.001. Epub 2011 Nov 21.
4
A clinical conundrum: Temporal bone metastases from lung adenocarcinoma.一个临床难题:来自肺腺癌的颞骨转移。
Am J Otolaryngol. 2023 Jul-Aug;44(4):103880. doi: 10.1016/j.amjoto.2023.103880. Epub 2023 Mar 28.
5
Atypical presentation of carcinoid tumor with unresolved right shoulder pain: a case report.类癌肿瘤伴右肩疼痛未缓解的非典型表现:一例报告
J Med Case Rep. 2014 May 7;8:142. doi: 10.1186/1752-1947-8-142.
6
Facial paralysis caused by metastasis of breast carcinoma to the temporal bone.乳腺癌转移至颞骨导致的面瘫。
J Chin Med Assoc. 2004 Nov;67(11):587-90.
7
Metastatic carcinoma of the temporal bone.颞骨转移性癌
Am J Otol. 1996 Sep;17(5):780-3.
8
[Carcinoma of the temporal bone--current diagnostic and therapeutic aspects].[颞骨癌——当前的诊断与治疗方面]
Laryngorhinootologie. 1995 Nov;74(11):666-72. doi: 10.1055/s-2007-997822.
9
Brain metastasis as the first manifestation of small cell lung cancer in a female adolescent.脑转移作为一名女性青少年小细胞肺癌的首发表现。
Lung Cancer. 2011 Aug;73(2):243-6. doi: 10.1016/j.lungcan.2011.04.018. Epub 2011 May 25.
10
[The interesting case -- case no. 68. Metastasis of a small-cell bronchial carcinoma to the parotid gland].[有趣的病例——病例编号68。小细胞支气管癌转移至腮腺]
Laryngorhinootologie. 2005 Feb;84(2):117-20. doi: 10.1055/s-2004-826220.

本文引用的文献

1
Clinical Characteristics of Temporal Bone Metastases.颞骨转移瘤的临床特征
Clin Exp Otorhinolaryngol. 2019 Feb;12(1):27-32. doi: 10.21053/ceo.2018.00171. Epub 2018 Jun 19.
2
Malignant tumors of the temporal bone - our experience.颞骨恶性肿瘤——我们的经验
Braz J Otorhinolaryngol. 2016 Jul-Aug;82(4):479-83. doi: 10.1016/j.bjorl.2015.09.010. Epub 2016 Jan 7.
3
State of the art in temporal bone malignancies.颞骨恶性肿瘤的最新进展。
Curr Opin Otolaryngol Head Neck Surg. 2014 Apr;22(2):154-65. doi: 10.1097/MOO.0000000000000035.
4
Two cases of temporal bone metastases as presenting sign of lung cancer.两例以颞骨转移为首发表现的肺癌病例。
Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Feb;129(1):54-7. doi: 10.1016/j.anorl.2011.07.001. Epub 2011 Nov 21.