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两例以颞骨转移为首发表现的肺癌病例。

Two cases of temporal bone metastases as presenting sign of lung cancer.

机构信息

Service d'ORL et chirurgie cervicofaciale, CHRU de Tours, boulevard Tonnellé, Tours, France.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Feb;129(1):54-7. doi: 10.1016/j.anorl.2011.07.001. Epub 2011 Nov 21.

Abstract

OBJECTIVE

To report the clinical and radiological features of temporal bone metastases and their association with primary lung cancer.

CASE REPORTS

Both patients complained of headache, cochlear signs or cranial nerve palsy. Computed tomography of the petrous temporal bones and magnetic resonance imaging showed an osteolytic lesion of the temporal bone. The preoperative work-up was completed by chest, abdomen and pelvis computed tomography and positron emission tomography. Bronchoscopic biopsies confirmed the diagnosis of lung cancer.

DISCUSSION/CONCLUSION: The discovery of an osteolytic lesion of the temporal bone requires an aetiological work-up, including the search for a lung tumour based on the hypothesis of temporal bone metastasis. Positron emission tomography should now be performed in the context of such lesions. Management consists of palliative chemotherapy and analgesic radiotherapy.

摘要

目的

报告颞骨转移瘤的临床和影像学特征及其与原发性肺癌的关系。

病例报告

两名患者均主诉头痛、耳蜗征或颅神经麻痹。岩骨颞骨的计算机断层扫描和磁共振成像显示颞骨溶骨性病变。术前检查完成了胸部、腹部和骨盆计算机断层扫描和正电子发射断层扫描。支气管镜活检证实了肺癌的诊断。

讨论/结论:发现颞骨溶骨性病变需要进行病因学检查,包括根据颞骨转移瘤的假说寻找肺部肿瘤。现在应该在这种病变的情况下进行正电子发射断层扫描。治疗包括姑息性化疗和止痛放疗。

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