A.I. Yevdokimov Moscow State University of Medicine and Dentistry, 20, p. 1 Delegatskaya St., 127473 Moscow, Russia.
Federal Scientific Research Centre "Crystallography and Photonics" Russian Academy of Sciences, 59 Leninskiy Prospekt, 119333 Moscow, Russia; Bauman Moscow State Technical University, 5/1 2-ya Baumanskaya St, 105005 Moscow, Russia.
Dent Mater. 2022 Jun;38(6):924-934. doi: 10.1016/j.dental.2022.03.003. Epub 2022 Mar 11.
To study the oxide layer stability of certified dental implants of system "P", made based on TiO alloy with carbon coating. To perform a comparative statistical analysis of the obtained data with the available data for the dental implants of systems "A" and "B".
X-ray microtomography and X-ray fluorescence analysis were used to study soft tissue biopsy specimens. Supernatants were studied by dynamic light scattering and transmission electron microscopy when simulating free emission of nanoscale metal oxide particles from the surface of dental implants as well as when simulating physical loading. A comparative analysis of three parameters of nanoscale particles was performed by statistical data analysis. The surface of the "P" system dental implant with surface treatment was analyzed by scanning electron microscopy.
Both free emission of nanoscale oxide layer particles and yield of nano- and microscale particles during simulation of physical load were confirmed. Statistically significant differences were noted in a comparative analysis of the size and frequency of occurrence of these particles in the supernatants obtained from the surfaces of three dental implant systems. The elemental composition of the particles and the composition and structure of the "P" system dental implants themselves were analyzed.
The developed method of dynamic light scattering can be used to compare the stability of the oxide layer of standardized medical products manufactured on the basis of the TiO alloy.
研究基于 TiO 合金和碳涂层的“P”系统认证牙科植入物的氧化层稳定性。对获得的数据与系统“A”和“B”的牙科植入物的现有数据进行比较统计分析。
使用 X 射线微断层扫描和 X 射线荧光分析研究软组织活检样本。通过动态光散射和透射电子显微镜研究模拟纳米级金属氧化物颗粒从牙科植入物表面自由释放以及模拟物理负荷时的上清液。通过统计数据分析对纳米级颗粒的三个参数进行了比较分析。通过扫描电子显微镜对经过表面处理的“P”系统牙科植入物的表面进行了分析。
确认了纳米级氧化层颗粒的自由释放以及在模拟物理负荷期间纳米级和微级颗粒的产量。对从三个牙科植入系统表面获得的上清液中这些颗粒的大小和出现频率进行比较分析时，发现了统计学上的显著差异。分析了颗粒的元素组成以及“P”系统牙科植入物本身的组成和结构。
所开发的动态光散射方法可用于比较基于 TiO 合金制造的标准化医疗产品的氧化层稳定性。
