Department of Inorganic Polymers, Petru Poni Institute of Macromolecular Chemistry, Iaşi, Romania.
Arch Pharm (Weinheim). 2022 Jun;355(6):e2100462. doi: 10.1002/ardp.202100462. Epub 2022 Mar 15.
Thiophene, as a member of the group of five-membered heterocycles containing one heteroatom, is one of the simplest heterocyclic systems. Many synthetic strategies allow the accurate positioning of various functionalities onto the thiophene ring. This review provides a comprehensive, systematic and detailed account of the developments in the field of antimicrobial compounds featuring at least one thiophene ring in their structure, over the last decade.
噻吩作为含有一个杂原子的五元杂环族的一员，是最简单的杂环体系之一。许多合成策略允许将各种官能团精确定位到噻吩环上。本篇综述全面、系统、详细地介绍了过去十年中在结构中至少具有一个噻吩环的抗菌化合物领域的发展。
