Bhatia Kulsajan, Solanki Smeet, Paes Bosco, Chan Anthony K C, Bhatt Mihir D
Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, New York.
Division of Pediatric Hematology/Oncology, McMaster Children's Hospital, McMaster University, Hamilton, Ontario, Canada.
Pediatr Blood Cancer. 2022 Jun;69(6):e29668. doi: 10.1002/pbc.29668. Epub 2022 Mar 15.
Among children, neonates have the highest incidence of thrombosis. We conducted a retrospective review of neonatal thrombosis, in a single intensive care unit (ICU) over 4.5 years. Among 4860 ICU admissions to our center, identified through the Canadian Neonatal Network database, 186 were associated with arterial and venous thrombosis involving 195 thrombotic sites. The neonatal thrombosis incidence was 38 per 1000 neonatal ICU admissions. We assessed patient characteristics and compared the association between risk factors and thrombosis. In the multivariate analysis, central venous catheters, sepsis, and respiratory distress syndrome were significant predictors of neonatal thrombosis.
在儿童中，新生儿的血栓形成发生率最高。我们对一个重症监护病房（ICU）4.5年期间的新生儿血栓形成情况进行了回顾性研究。通过加拿大新生儿网络数据库确定，在我们中心的4860例ICU入院病例中，有186例与动脉和静脉血栓形成相关，涉及195个血栓形成部位。新生儿血栓形成的发生率为每1000例新生儿ICU入院病例中有38例。我们评估了患者特征，并比较了危险因素与血栓形成之间的关联。在多变量分析中，中心静脉导管、败血症和呼吸窘迫综合征是新生儿血栓形成的重要预测因素。
