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冷冻消融对小儿漏斗胸修复的影响。

Impact of Cryoablation on Pectus Excavatum Repair in Pediatric Patients.

作者信息

Clark Rachael A, Jacobson Jillian C, Singhal Amogh, Alder Adam C, Chung Dai H, Pandya Samir R

机构信息

From the Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX.

出版信息

J Am Coll Surg. 2022 Apr 1;234(4):484-492. doi: 10.1097/XCS.0000000000000103.

Abstract

BACKGROUND

Minimally invasive repair of pectus excavatum (MIRPE) involves placement of a transthoracic, retrosternal support bar under thoracoscopic guidance. Despite its minimally invasive technical approach, postoperative pain is a significant morbidity that often results in increased length of stay. Multi-modal pain control strategies have been used in the past with limited success. Recently, the use of intraoperative intercostal nerve cryoablation (CA) has been added. In the present study, we aim to evaluate the effects of CA on postoperative pain control, opioid requirements, and perioperative outcomes.

STUDY DESIGN

A single-center, retrospective chart review of all patients (less than 18 years old) who underwent MIRPE from 2009 to 2020 was performed. CA was started in June 2018. Data collection included demographics, preoperative characteristics, intraoperative findings, and postoperative outcomes. We hypothesized that CA would be associated with improved pain scores, lower doses of total inpatient opioid requirement, and shorter length of stay (LOS).

RESULTS

One hundred sixty-one patients met inclusion criteria: 75 underwent intraoperative CA and 86 underwent MIRPE without CA (NCA group). CA significantly decreased median LOS from 4 days in NCA to 2 days; the use of CA was the only significant predictor of LOS on linear regression. CA was also associated with decreased total PCA, intravenous opioid, and oral opioid dosages. There was no difference in inpatient pain scores and a slight increase in mean procedure time. However, CA was associated with significantly decreased postoperative complications.

CONCLUSIONS

The use of cryoablation during MIRPE significantly decreases LOS, perioperative opioid requirements, and postoperative complications, with a minimal increase in operative time. Cryoablation is an effective pain control modality in the surgical management of chest wall deformities in children.

摘要

背景

漏斗胸微创修复术(MIRPE)包括在胸腔镜引导下放置经胸、胸骨后支撑杆。尽管其技术方法具有微创性,但术后疼痛是一种显著的并发症,常导致住院时间延长。过去曾使用多模式疼痛控制策略,但效果有限。最近,术中肋间神经冷冻消融术(CA)被应用。在本研究中,我们旨在评估CA对术后疼痛控制、阿片类药物需求及围手术期结局的影响。

研究设计

对2009年至2020年接受MIRPE的所有(小于18岁)患者进行单中心回顾性图表审查。CA于2018年6月开始应用。数据收集包括人口统计学、术前特征、术中发现及术后结局。我们假设CA将与疼痛评分改善、住院期间总阿片类药物需求剂量降低及住院时间(LOS)缩短相关。

结果

161例患者符合纳入标准:75例接受术中CA,86例接受无CA的MIRPE(非CA组)。CA显著降低了中位住院时间,从非CA组的4天降至2天;CA的使用是线性回归中住院时间的唯一显著预测因素。CA还与总PCA、静脉阿片类药物和口服阿片类药物剂量的降低相关。住院疼痛评分无差异,平均手术时间略有增加。然而,CA与术后并发症显著减少相关。

结论

MIRPE术中使用冷冻消融术可显著缩短住院时间、降低围手术期阿片类药物需求及减少术后并发症,手术时间增加极少。冷冻消融术是儿童胸壁畸形手术治疗中一种有效的疼痛控制方式。

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