University of Utah School of Medicine, 100 North Mario Capechi Drive, Salt Lake City, UT, 84103-0000, United States.
Department of Surgery, Division of Pediatric Surgery, University of Utah, Salt Lake City, UT, United States.
Pediatr Surg Int. 2024 Oct 3;40(1):260. doi: 10.1007/s00383-024-05838-2.
Our institution recently transitioned from paravertebral nerve blocks (PVBs) to intercostal nerve cryoablation (INC) for pain control following minimally invasive repair of pectus excavatum (MIRPE). This study aimed to determine how INC affected the operative time, length of stay, complication rates, inpatient opioid use, and outpatient prescription of opioids at a single center.
A retrospective review was performed at a single pediatric referral center of all patients who underwent MIRPE between 2018 and 2023. Patient demographics, operative details, and perioperative course were collected. The use of INC versus PVB was recorded. Univariate analyses were performed using Wilcoxon rank sum tests for continuous variables and chi-squared tests for categorical variables.
255 patients were included with a median age of 15 years, median BMI of 18.50 kg/m, and median Haller index of 4.40. INC was utilized in 41% (105/255), and 59% (150/255) received PVB. The two groups did not differ significantly in BMI, Haller index, or complications, though the INC patients were older by 1 year (15.0 vs. 16.0, p = 0.034). INC was associated with an increased operative time (INC: 92 min vs. PVB: 67 min, p < 0.001), decreased length of stay (3 vs. 4 days, p = < 0.001), more than twofold decrease in inpatient opioids per day (INC: 16 MME vs. PVB: 41 MME, p < 0.001), and a fourfold decrease in the amount of opioids prescribed at discharge (INC: 90 MME vs. PVB: 390 MME, p < 0.001).
INC after MIRPE significantly decreased both the inpatient opioid utilization and our outpatient prescribing practices while also decreasing our overall length of stay without increasing complications.
Level III.
我们机构最近将微创漏斗胸修复术(MIRPE)后的疼痛控制方法从椎旁神经阻滞(PVB)转变为肋间神经冷冻消融(INC)。本研究旨在确定 INC 在单中心对手术时间、住院时间、并发症发生率、住院内阿片类药物使用和门诊阿片类药物处方的影响。
对单儿科转诊中心 2018 年至 2023 年间所有接受 MIRPE 的患者进行回顾性研究。收集患者的人口统计学资料、手术细节和围手术期过程。记录 INC 与 PVB 的使用情况。连续变量采用 Wilcoxon 秩和检验,分类变量采用卡方检验进行单因素分析。
共纳入 255 例患者,中位年龄 15 岁,中位 BMI 为 18.50kg/m,中位 Haller 指数为 4.40。41%(105/255)的患者接受 INC,59%(150/255)的患者接受 PVB。两组在 BMI、Haller 指数或并发症方面无显著差异,但 INC 患者年龄大 1 岁(INC:15.0 岁 vs. PVB:16.0 岁,p=0.034)。INC 与手术时间延长(INC:92 分钟 vs. PVB:67 分钟,p<0.001)、住院时间缩短(3 天 vs. 4 天,p<0.001)、住院内阿片类药物用量减少两倍以上(INC:16MME vs. PVB:41MME,p<0.001)和出院时阿片类药物处方量减少四倍(INC:90MME vs. PVB:390MME,p<0.001)有关。
MIRPE 后 INC 显著减少了住院内阿片类药物的使用和我们的门诊处方量,同时缩短了总住院时间,而不会增加并发症。
III 级。