痴呆的发病率、患病率、死亡率和差异：一项涉及 430 万人的人群关联电子健康记录研究。
Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals.
机构信息
Department of Health Informatics, Health Data Research UK, London, UK.
Department of Health Informatics, University College London, London, UK.
出版信息
Alzheimers Dement. 2023 Jan;19(1):123-135. doi: 10.1002/alz.12635. Epub 2022 Mar 15.
INTRODUCTION
We report dementia incidence, comorbidities, reasons for health-care visits, mortality, causes of death, and examined dementia patterns by relative deprivation in the UK.
METHOD
A longitudinal cohort analysis of linked electronic health records from 4.3 million people in the UK was conducted to investigate dementia incidence and mortality. Reasons for hospitalization and causes of death were compared in individuals with and without dementia.
RESULTS
From 1998 to 2016 we observed 145,319 (3.1%) individuals with incident dementia. Repeated hospitalizations among senior adults for infection, unknown morbidity, and multiple primary care visits for chronic pain were observed prior to dementia diagnosis. Multiple long-term conditions are present in half of the individuals at the time of diagnosis. Individuals living in high deprivation areas had higher dementia incidence and high fatality.
DISCUSSION
There is a considerable disparity of dementia that informs priorities of prevention and provision of patient care.
简介
我们报告了英国的痴呆症发病率、合并症、就医原因、死亡率、死因以及相对贫困对痴呆症模式的影响。
方法
对英国 430 万人的电子健康记录进行了一项纵向队列分析，以调查痴呆症的发病率和死亡率。比较了有和没有痴呆症的个体的住院原因和死因。
结果
1998 年至 2016 年，我们观察到 145319 名（3.1%）新发痴呆症患者。在诊断痴呆症之前，老年人因感染、不明病因和慢性疼痛多次到初级保健就诊。一半的患者在诊断时已经存在多种长期疾病。生活在高贫困地区的人痴呆症发病率更高，死亡率也更高。
讨论
痴呆症存在相当大的差异，这为预防和提供患者护理的优先事项提供了信息。
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