• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

COVID-19 住院治疗的埃塞俄比亚儿童:特征和预后情况。

COVID-19 in hospitalized Ethiopian children: characteristics and outcome profile.

机构信息

Millennium COVID-19 Care Center, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

出版信息

Pan Afr Med J. 2022 Jan 7;41:16. doi: 10.11604/pamj.2022.41.16.29414. eCollection 2022.

DOI:10.11604/pamj.2022.41.16.29414
PMID:35291361
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8895553/
Abstract

INTRODUCTION

considering the number of people affected and the burden to the health care system due to the coronavirus pandemic, there is still a gap in understanding the disease better leaving a space for new evidence to be filled by researchers. This scarcity of evidence is observed especially among children with the virus. Therefore, this study aimed to assess the characteristics and outcome profile of children with COVID-19 admitted to Millennium COVID-19 Care Center in Ethiopia.

METHODS

a prospective cohort study was conducted among 90 children with COVID-19 who were admitted from June 23 to September 17, 2020. Data were summarized using frequency tables, mean ± standard deviation or median with inter quartile range values. A chi-square test/Fischer´s exact test was used to compare disease severity between groups.

RESULTS

the median age of the participants was 15 years and 57 were females. The most common reported route of disease transmission was through close contact with a diagnosed person (41/90). Only three had a history of pre-existing comorbid illness. One-third (31/90) had one or more symptoms at diagnosis, the most common being cough (20/90). Among the 90 patients, 59 were asymptomatic, 14 had mild disease and the rest 17 had moderate disease. Based on the chi-square/Fischer´s exact test result, no statistically significant difference was observed between the age groups and sex.

CONCLUSION

pediatric patients seemed to have a milder disease presentation and a favorable outcome compared to other countries report and also the adult pattern observed in our country.

摘要

简介

考虑到冠状病毒大流行对受影响人数和医疗保健系统的负担,人们对该病的了解仍存在差距,为研究人员提供了新的证据填补空间。在患有该病毒的儿童中,这种证据的缺乏尤为明显。因此,本研究旨在评估在埃塞俄比亚千禧年 COVID-19 护理中心住院的 COVID-19 患儿的特征和预后情况。

方法

在 2020 年 6 月 23 日至 9 月 17 日期间,对 90 名 COVID-19 患儿进行了前瞻性队列研究。使用频数表、平均值±标准差或中位数和四分位间距值对数据进行总结。使用卡方检验/Fisher 确切检验比较组间疾病严重程度。

结果

参与者的中位年龄为 15 岁,57 人为女性。报告的最常见疾病传播途径是与确诊患者密切接触(41/90)。仅有 3 人有既往合并症病史。三分之一(31/90)在诊断时有一个或多个症状,最常见的是咳嗽(20/90)。在 90 例患者中,59 例为无症状,14 例为轻症,其余 17 例为中症。基于卡方/Fisher 确切检验结果,年龄组和性别之间无统计学差异。

结论

与其他国家的报告以及我们国家观察到的成人模式相比,儿科患者的疾病表现似乎较轻,预后较好。

相似文献

1
COVID-19 in hospitalized Ethiopian children: characteristics and outcome profile.COVID-19 住院治疗的埃塞俄比亚儿童:特征和预后情况。
Pan Afr Med J. 2022 Jan 7;41:16. doi: 10.11604/pamj.2022.41.16.29414. eCollection 2022.
2
Virtualized clinical studies to assess the natural history and impact of gut microbiome modulation in non-hospitalized patients with mild to moderate COVID-19 a randomized, open-label, prospective study with a parallel group study evaluating the physiologic effects of KB109 on gut microbiota structure and function: a structured summary of a study protocol for a randomized controlled study.用于评估非住院轻中度 COVID-19 患者肠道微生物组调节的自然史和影响的虚拟化临床研究:一项随机、开放标签、前瞻性研究,平行组研究评估 KB109 对肠道微生物组结构和功能的生理影响:一项随机对照研究方案的结构化总结。
Trials. 2021 Apr 2;22(1):245. doi: 10.1186/s13063-021-05157-0.
3
Children hospitalized for COVID-19 during the first winter of the pandemic in Buenos Aires, Argentina.在阿根廷布宜诺斯艾利斯大流行的第一个冬天,因 COVID-19 住院的儿童。
Bol Med Hosp Infant Mex. 2021 Dec 15;78(6):501-505. doi: 10.24875/BMHIM.21000039.
4
Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19: A structured summary of a study protocol for a randomised controlled trial.COVID-19 住院成人患者使用伊马替尼的安全性和疗效:一项随机对照试验研究方案的结构化总结。
Trials. 2020 Oct 28;21(1):897. doi: 10.1186/s13063-020-04819-9.
5
Evaluation of changes in pediatric emergency department utilization during COVID-19 pandemic.评估 COVID-19 大流行期间儿科急诊就诊人次的变化。
Arch Pediatr. 2021 Nov;28(8):677-682. doi: 10.1016/j.arcped.2021.09.014. Epub 2021 Oct 6.
6
Clinical Characteristics and Outcome of Hospitalized COVID-19 Patients in a MERS-CoV Endemic Area.在中东呼吸综合征冠状病毒流行地区住院的 COVID-19 患者的临床特征和转归。
J Epidemiol Glob Health. 2020 Sep;10(3):214-221. doi: 10.2991/jegh.k.200806.002.
7
Patients assisted at the Department of Medicine of a pediatric hospital at the beginning of the COVID-19 pandemic in Buenos Aires, Argentina.在阿根廷布宜诺斯艾利斯新冠疫情初期,一家儿科医院内科接受治疗的患者。
Arch Argent Pediatr. 2020 Dec;118(6):418-426. doi: 10.5546/aap.2020.eng.423.
8
Longitudinal Household Assessment of Respiratory Illness in Children and Parents During the COVID-19 Pandemic.COVID-19 大流行期间儿童及其父母呼吸道疾病的纵向家庭评估。
JAMA Netw Open. 2022 Oct 3;5(10):e2237522. doi: 10.1001/jamanetworkopen.2022.37522.
9
Characteristics, Treatment Outcomes and Role of Hydroxychloroquine among 522 COVID-19 hospitalized patients in Jaipur City: An Epidemio-Clinical Study.斋浦尔市522例COVID-19住院患者的羟氯喹特性、治疗结果及作用:一项流行病学临床研究
J Assoc Physicians India. 2020 Jun;68(6):13-19.
10
Clinical Characteristics and Outcome of Pediatric COVID-19 Patients in Ethiopia During the Early COVID-19 Pandemic: A Prospective Cohort Study.埃塞俄比亚儿童新冠疫情早期新冠病毒肺炎患者的临床特征及转归:一项前瞻性队列研究
Pediatric Health Med Ther. 2022 May 5;13:165-174. doi: 10.2147/PHMT.S359333. eCollection 2022.

引用本文的文献

1
Causal Inference of the Effect of Vaccination on COVID-19 Disease Severity and Need for Intensive Care Unit Admission Among Hospitalized Patients in an African Setting.非洲地区住院患者中疫苗接种对新冠病毒疾病严重程度及重症监护病房收治需求影响的因果推断
Cureus. 2024 Aug 25;16(8):e67719. doi: 10.7759/cureus.67719. eCollection 2024 Aug.
2
Clinical epidemiology of COVID-19 among hospitalized children in rural western Kenya.肯尼亚西部农村地区住院儿童新冠病毒病的临床流行病学
PLOS Glob Public Health. 2023 Jun 14;3(6):e0002011. doi: 10.1371/journal.pgph.0002011. eCollection 2023.
3
Clinical Characteristics and Outcome of Pediatric COVID-19 Patients in Ethiopia During the Early COVID-19 Pandemic: A Prospective Cohort Study.埃塞俄比亚儿童新冠疫情早期新冠病毒肺炎患者的临床特征及转归:一项前瞻性队列研究
Pediatric Health Med Ther. 2022 May 5;13:165-174. doi: 10.2147/PHMT.S359333. eCollection 2022.
4
Distinct Characteristics of COVID-19 Infection in Children.儿童新冠病毒感染的独特特征。
Front Pediatr. 2021 Mar 4;9:619738. doi: 10.3389/fped.2021.619738. eCollection 2021.

本文引用的文献

1
Characteristics and outcome profile of hospitalized African patients with COVID-19: The Ethiopian context.住院的非洲 COVID-19 患者的特征和预后概况:埃塞俄比亚的情况。
PLoS One. 2021 Nov 9;16(11):e0259454. doi: 10.1371/journal.pone.0259454. eCollection 2021.
2
Duration of Supplemental Oxygen Requirement and Predictors in Severe COVID-19 Patients in Ethiopia: A Survival Analysis.在埃塞俄比亚,严重 COVID-19 患者的补充氧气需求持续时间和预测因素:生存分析。
Ethiop J Health Sci. 2021 Jul;31(4):699-708. doi: 10.4314/ejhs.v31i4.3.
3
Predictors of death in severe COVID-19 patients at millennium COVID-19 care center in Ethiopia: a case-control study.在埃塞俄比亚千禧年 COVID-19 护理中心,严重 COVID-19 患者死亡的预测因素:一项病例对照研究。
Pan Afr Med J. 2021 Apr 12;38:351. doi: 10.11604/pamj.2021.38.351.28831. eCollection 2021.
4
Clinical Experience With Severe Acute Respiratory Syndrome Coronavirus 2-Related Illness in Children: Hospital Experience in Cape Town, South Africa.儿童严重急性呼吸综合征冠状病毒 2 相关疾病的临床经验:南非开普敦的医院经验。
Clin Infect Dis. 2021 Jun 15;72(12):e938-e944. doi: 10.1093/cid/ciaa1666.
5
COVID-19 Trends Among School-Aged Children - United States, March 1-September 19, 2020.2020 年 3 月 1 日至 9 月 19 日美国学龄儿童中的 COVID-19 趋势。
MMWR Morb Mortal Wkly Rep. 2020 Oct 2;69(39):1410-1415. doi: 10.15585/mmwr.mm6939e2.
6
Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study.英国因 COVID-19 住院的儿童和青少年的临床特征:前瞻性多中心观察队列研究。
BMJ. 2020 Aug 27;370:m3249. doi: 10.1136/bmj.m3249.
7
Epidemiological and clinical features of pediatric COVID-19.儿童 COVID-19 的流行病学和临床特征。
BMC Med. 2020 Aug 6;18(1):250. doi: 10.1186/s12916-020-01719-2.
8
Clinical characteristics of COVID-19 in children: A systematic review.儿童 COVID-19 的临床特征:系统评价。
Pediatr Pulmonol. 2020 Oct;55(10):2565-2575. doi: 10.1002/ppul.24991. Epub 2020 Aug 4.
9
Clinical Characteristics of Children With COVID-19: A Meta-Analysis.新型冠状病毒肺炎患儿的临床特征:一项荟萃分析
Front Pediatr. 2020 Jul 3;8:431. doi: 10.3389/fped.2020.00431. eCollection 2020.
10
Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units.美国和加拿大儿科重症监护病房收治的儿童 2019 年冠状病毒病(COVID-19)感染的特征和结局。
JAMA Pediatr. 2020 Sep 1;174(9):868-873. doi: 10.1001/jamapediatrics.2020.1948.