From the Discipline of Orthopaedic Surgery, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Nfld.
Can J Surg. 2022 Mar 15;65(2):E188-E192. doi: 10.1503/cjs.017520. Print 2022 Mar-Apr.
Previous research has shown increases in length of stay (LOS), morbidity and mortality when the standard for surgical fixation of hip fracture of 48 hours is not met. However, few investigators have analyzed LOS as a primary outcome, and most used time of diagnosis as opposed to time of fracture as the reference point. We examined the effect of time to surgical fixation of hip fracture, measured from time of fracture, on length of hospital stay; the secondary outcome was average 1-year mortality.
We conducted a retrospective cohort study of patients presenting to 1 of 2 tertiary care centres in St. John's, Newfoundland and Labrador, Canada, with a hip fracture from Jan. 1, 2014, to Dec. 31, 2018. We analyzed 3 groups based on timing of surgical fixation after fracture: less than 24 hours (group 1), 24-48 hours (group 2) and more than 48 hours (group 3). We assessed statistical significance using 1-way analysis of variance.
Of the 692 patients included in the study, 212 (30.6%) were in group 1, 360 (52.0%) in group 2 and 120 (17.3%) in group 3. A delay to surgical fixation exceeding 48 hours was associated with a significantly longer LOS, by an average of 2.9 and 2.8 days compared to groups 1 and 2, respectively ( = 0.04); there was no significant difference in LOS between groups 1 and 2. A significant difference in average 1-year mortality was observed between groups 1 (11%) and 3 (26%) ( = 0.004), and groups 2 (13%) and 3 ( = 0.009).
Surgical fixation beyond 48 hours after hip fracture resulted in significantly increased LOS and 1-year mortality. Further research should be conducted to evaluate reasons for delays to surgery and the effects of these delays on time to surgical fixation as measured from time of fracture.
先前的研究表明,如果未能在 48 小时内达到髋关节骨折的手术固定标准,住院时间(LOS)、发病率和死亡率会增加。然而,很少有研究人员将 LOS 作为主要结果进行分析,而且大多数人使用诊断时间而不是骨折时间作为参考点。我们检查了从骨折发生时间起,测量到的髋关节骨折手术固定时间对住院时间的影响;次要结果是平均 1 年死亡率。
我们对 2014 年 1 月 1 日至 2018 年 12 月 31 日期间在加拿大纽芬兰省圣约翰市的 2 个三级护理中心就诊的髋部骨折患者进行了回顾性队列研究。我们根据骨折后手术固定的时间将患者分为 3 组:小于 24 小时(第 1 组)、24-48 小时(第 2 组)和超过 48 小时(第 3 组)。我们使用单向方差分析评估统计学意义。
在纳入研究的 692 名患者中,212 名(30.6%)在第 1 组,360 名(52.0%)在第 2 组,120 名(17.3%)在第 3 组。与第 1 组和第 2 组相比,手术固定时间超过 48 小时与 LOS 显著延长相关,平均分别延长 2.9 天和 2.8 天( = 0.04);第 1 组和第 2 组之间 LOS 无显著差异。第 1 组(11%)和第 3 组(26%)( = 0.004)以及第 2 组(13%)和第 3 组( = 0.009)之间的平均 1 年死亡率存在显著差异。
髋关节骨折后超过 48 小时进行手术固定会导致 LOS 和 1 年死亡率显著增加。应进一步研究导致手术延迟的原因,以及这些延迟对从骨折发生时间起测量的手术固定时间的影响。