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手术延迟对髋部骨折患者预后的影响:192例患者的回顾性多因素分析

Effect of surgical delay on outcome in hip fracture patients: a retrospective multivariate analysis of 192 patients.

作者信息

Verbeek D O F, Ponsen K J, Goslings J C, Heetveld M J

机构信息

Trauma Unit, Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.

出版信息

Int Orthop. 2008 Feb;32(1):13-8. doi: 10.1007/s00264-006-0290-9. Epub 2007 Jan 12.

Abstract

Previous studies have not demonstrated consistent results on the effect of surgical delay on outcome. This study investigated the association between the delay to surgery and the development of postoperative complications, length of hospital stay (LOS) and one-year mortality. Patients that underwent surgery for a hip fracture in a two-year period were included in a retrospective study. Uni- and multivariate regression analysis was performed in 192 hip fracture patients. There was a trend towards fewer postoperative complications (P = 0.064; multivariate regression, MR) and shorter LOS (P = 0.088; MR) in patients with a delay of less than one day to surgery. No association between surgical delay and one-year mortality was found in the population as a whole (P = 0.632; univariate regression, UR). Delay to surgery beyond one day was associated with an increased risk of infectious complications (P = 0.004; MR). In ASA I and II class patients, operation beyond one day from admission was associated with an increased risk of one-year mortality (P = 0.03; MR) and more postoperative infectious complications (P = 0.02; MR). The trends towards fewer complications and shorter LOS suggest that early surgery (within one day from admission) is beneficial for hip fracture patients who are able to undergo an operation.

摘要

以往的研究尚未就手术延迟对预后的影响得出一致的结果。本研究调查了手术延迟与术后并发症的发生、住院时间(LOS)和一年死亡率之间的关联。对在两年期间接受髋部骨折手术的患者进行了一项回顾性研究。对192例髋部骨折患者进行了单因素和多因素回归分析。手术延迟少于一天的患者术后并发症较少(P = 0.064;多因素回归,MR)且住院时间较短(P = 0.088;MR),存在这种趋势。在总体人群中未发现手术延迟与一年死亡率之间存在关联(P = 0.632;单因素回归,UR)。手术延迟超过一天与感染性并发症风险增加相关(P = 0.004;MR)。在ASA I和II级患者中,入院后一天以上进行手术与一年死亡率风险增加(P = 0.03;MR)和更多术后感染性并发症(P = 0.02;MR)相关。并发症较少和住院时间较短的趋势表明,早期手术(入院后一天内)对能够接受手术的髋部骨折患者有益。

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