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2
Impact of COVID-19 pandemic on lower urinary tract symptoms in patients with benign prostatic hyperplasia and predictors of urine retention in such patients.2019冠状病毒病大流行对良性前列腺增生患者下尿路症状的影响及此类患者尿潴留的预测因素
Low Urin Tract Symptoms. 2022 Jan;14(1):41-46. doi: 10.1111/luts.12407. Epub 2021 Aug 26.
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Is coronavirus disease 2019 associated with indicators of long-term bladder dysfunction?2019 年冠状病毒病是否与长期膀胱功能障碍的指标有关?
Neurourol Urodyn. 2021 Jun;40(5):1200-1206. doi: 10.1002/nau.24682. Epub 2021 May 4.
4
Bladder and bowel incontinence in COVID-19.新型冠状病毒肺炎中的膀胱和肠道失禁
J Med Virol. 2021 May;93(5):2609-2610. doi: 10.1002/jmv.26849. Epub 2021 Feb 19.
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COVID-19 inflammation results in urine cytokine elevation and causes COVID-19 associated cystitis (CAC).COVID-19 炎症导致尿液细胞因子升高,并导致 COVID-19 相关性膀胱炎(CAC)。
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BMJ Case Rep. 2020 Nov 17;13(11):e236625. doi: 10.1136/bcr-2020-236625.
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Urinary Frequency as a Possibly Overlooked Symptom in COVID-19 Patients: Does SARS-CoV-2 Cause Viral Cystitis?新冠病毒感染患者的尿频:新冠病毒是否会导致病毒性膀胱炎?
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儿童 COVID-19 后尿动力学证实的下尿路功能障碍:病例系列。

Urodynamically proven lower urinary tract dysfunction in children after COVID-19: A case series.

机构信息

Division of Pediatric Urology, Department of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Department of Urology, Koç University School of Medicine, Istanbul, Turkey.

出版信息

Low Urin Tract Symptoms. 2022 Jul;14(4):301-304. doi: 10.1111/luts.12436. Epub 2022 Mar 15.

DOI:10.1111/luts.12436
PMID:35293147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9115155/
Abstract

CASE

Since the declaration of COVID-19 as a pandemic, other unexpected symptoms related to the infection besides the respiratory system have been reported. Although a few case reports have revealed that adult patients with COVID-19 also complained of urinary frequency and nocturia, the exact pathophysiology is still unclear. In this case series, we present three children aged 14 to 17 years with urodynamically proven lower urinary tract dysfunction (LUTD) following COVID-19.

OUTCOME

None of the patients had constipation or bowel disorder before the diagnosis of COVID-19. In addition, neurological examination and related imaging revealed no signs of etiological factors. The median time from diagnosis of COVID-19 infection to the onset of lower urinary tract symptoms was 3 months. Incomplete bladder emptying/urinary retention supported by increased bladder compliance, high post-micturition residual urine volumes, and absence of detrusor pressure increase during the voiding phase in the pressure flow study (acontractile detrusor in two patients and hypocontractile detrusor in one patient) were observed.

CONCLUSION

We observed that LUTD (eg, incomplete bladder emptying, urinary retention) can be prominent some time after the diagnosis of COVID-19. Even though psychogenic or neurogenic causes may not be excluded completely, clinicians should be aware of a recent COVID-19 infection in children with sudden-onset LUTD.

摘要

病例

自 COVID-19 被宣布为大流行以来,除了呼吸系统之外,与感染相关的其他意外症状也有报道。尽管少数病例报告表明,患有 COVID-19 的成年患者也抱怨尿频和夜尿症,但确切的病理生理学仍不清楚。在本病例系列中,我们介绍了 3 名 14 至 17 岁的儿童,他们在 COVID-19 后经尿动力学证实存在下尿路功能障碍(LUTD)。

结果

在 COVID-19 诊断之前,这些患者均无便秘或肠道紊乱。此外,神经系统检查和相关影像学检查未发现病因因素的迹象。从 COVID-19 感染诊断到下尿路症状发作的中位时间为 3 个月。压力流研究中观察到膀胱顺应性增加、排尿后残余尿量增加和逼尿肌压力在排尿期无增加(两名患者为无收缩性逼尿肌,一名患者为低收缩性逼尿肌),提示存在不完全排空/尿潴留。

结论

我们观察到 LUTD(例如,不完全排空膀胱、尿潴留)可能在 COVID-19 诊断后一段时间内明显出现。即使不能完全排除心理或神经源性原因,临床医生也应该注意到儿童突然出现 LUTD 与近期 COVID-19 感染有关。