Fundação Oswaldo Cruz, Laboratório de Referência Nacional em Vetores das Riquetsioses, Rio de Janeiro, Rio de Janeiro, Brazil.
Secretaria Municipal de Saúde, Paraty, Rio de Janeiro, Brazil.
Rev Inst Med Trop Sao Paulo. 2022 Mar 11;64:e22. doi: 10.1590/S1678-9946202264022. eCollection 2022.
Spotted fever (SF) is a tick-borne zoonosis caused by bacteria of the genus Rickettsia . The disease varies in severity from mild clinical forms to severe cases. In Brazil, Rickettsia rickettsii SF is the most serious rickettsiosis and can result in death if not diagnosed and treated at the onset of symptoms. The SF mild form is caused by Rickettsia parkeri strain Atlantic Rainforest, and this etiological agent has been reported in the South, Southeast and Northeast regions of the country, in areas of preserved or little antropized Atlantic Rainforest. Amblyomma ovale is the proven vector and dogs are the hosts associated with the bioagent cycle. During a SF case investigation in Paraty municipality, Rio de Janeiro State, an Atlantic Rainforest biome area in Southeastern Brazil, the human pathogen R. parkeri strain Atlantic Rainforest was detected by PCR in a sample of human skin inoculation eschar and in a female A. ovale tick collected from a dog. These results expand the known area of occurrence of this mild form rickettsiosis in Brazil. In addition, the results of the present study indicate the importance of implementing programs to control canine ectoparasites and to raise awareness of the risks of infection, signs and symptoms of SF caused by R. parkeri strain Atlantic Rainforest.
斑点热（SF）是一种由立克次体属细菌引起的蜱媒传染病。该疾病的严重程度从轻度临床形式到严重病例不等。在巴西，落矶山斑点热（SF）是最严重的立克次体病，如果不在症状出现时诊断和治疗，可能导致死亡。SF 的轻度形式是由拉氏立克次体（Rickettsia parkeri）菌株大西洋雨林引起的，这种病原体已在该国南部、东南部和东北部地区以及受保护或受人为干扰较少的大西洋雨林地区报告过。卵圆硬蜱（Amblyomma ovale）是已知的传播媒介，狗是与生物剂循环相关的宿主。在巴西东南部大西洋雨林生物群落地区的里约热内卢州帕拉蒂市进行的一次 SF 病例调查中，通过 PCR 在人类皮肤接种焦痂样本和从狗身上采集的雌性卵圆硬蜱中检测到人类病原体拉氏立克次体（R. parkeri）菌株大西洋雨林。这些结果扩大了巴西这种轻度立克次体病的已知发生区域。此外，本研究结果表明，实施控制犬类外寄生虫和提高对由拉氏立克次体（R. parkeri）菌株大西洋雨林引起的 SF 感染风险、症状和体征的认识的计划非常重要。
