Department of Parasitology and Medical Entomology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, Kosti 27711, Sudan.
Department of Haematology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, Kosti 27711, Sudan.
Ann Parasitol. 2021;67(4):789-794. doi: 10.17420/ap6704.397.
Cryptosporidiosis is an illness caused by a protozooan parasite Cryptosporidium. Cryptosporidium species are an opportunistic pathogens cause a diarrheal disease worldwide, and can be more severe in immunocompromized patients. Until now, a little data have been available on its prevalence rate among haemodialysis patients in Sudan. Therefore, this article was designed to examine the prevalence of Cryptosporidium among hemodialysis Sudanese patients attending hemodialysis center at Kosti Teaching Hospital. A case-control study including one-hundred and twelve hemodialysis patients between November 2016 and January 2017 have been conducted. For the control group, we include one-hundred and twelve normal population. A total of two-hundred and twenty-four stool samples were collected. The stool samples were processed and examined using the modified Ziehl-Neelsen (ZN) staining method. High Cryptosporidium prevalence of 14/112 (12.5%) was detected in hemodialysis patients compare to the normal individuals 3/112 (2.7%). There was no correlation between the prevalence of Cryptosporidium infection with the age, sex, and the duration of dialysis (P>0.05). Therefore, an early detection and prompt treatment of Cryptosporidium infected hemodialysis patients is crucial.
隐孢子虫病是由原生动物寄生虫隐孢子虫引起的疾病。隐孢子虫种类是一种机会性病原体，在全球范围内引起腹泻病，并且在免疫功能低下的患者中可能更为严重。到目前为止，有关苏丹血液透析患者中隐孢子虫流行率的数据很少。因此，本文旨在检查在科斯蒂教学医院血液透析中心接受血液透析的苏丹患者中隐孢子虫的流行率。一项病例对照研究包括 2016 年 11 月至 2017 年 1 月期间的 112 名血液透析患者。对于对照组，我们包括 112 名正常人群。共采集了 224 份粪便样本。使用改良的齐尔-尼尔森（ZN）染色法处理和检查粪便样本。与正常个体 3/112（2.7%）相比，血液透析患者中高隐孢子虫的患病率为 14/112（12.5%）。隐孢子虫感染的患病率与年龄、性别和透析时间无相关性（P>0.05）。因此，早期发现和及时治疗感染隐孢子虫的血液透析患者至关重要。
