• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

原发性阿米巴脑膜脑炎：离子液体对抗食脑变形虫的潜在应用？

Primary Amoebic Meningoencephalitis: Potential Application of Ionic Liquids Against Brain-Eating Amoebae?

机构信息

College of Arts and Sciences, American University of Sharjah, Sharjah, United Arab Emirates.

College of Engineering, American University of Sharjah, Sharjah, United Arab Emirates.

出版信息

Acta Parasitol. 2022 Jun;67(2):1032-1034. doi: 10.1007/s11686-022-00532-6. Epub 2022 Mar 16.

DOI:10.1007/s11686-022-00532-6
PMID:35294972
Abstract

Naegleria fowleri, a well-known brain-eating amoeba, induces high mortality with no available effective treatment. Ionic liquids are compounds that contain a variety of cations and anions that can be tailored to specific applications. Based on the biological, chemical and physical properties of these ionic liquids, this work proposes the use of ionic liquids as novel anti-Naegleria fowleri biocides.

摘要

福氏耐格里阿米巴原虫，一种众所周知的食脑阿米巴，可导致高死亡率且目前尚无有效的治疗方法。离子液体是含有各种阳离子和阴离子的化合物，可以根据特定的应用进行定制。基于这些离子液体的生物学、化学和物理性质，本研究提出将离子液体用作新型抗福氏耐格里阿米巴原虫杀菌剂。

相似文献

1
Primary Amoebic Meningoencephalitis: Potential Application of Ionic Liquids Against Brain-Eating Amoebae?原发性阿米巴脑膜脑炎：离子液体对抗食脑变形虫的潜在应用？
Acta Parasitol. 2022 Jun;67(2):1032-1034. doi: 10.1007/s11686-022-00532-6. Epub 2022 Mar 16.
2
Identification of Naegleria fowleri proteins linked to primary amoebic meningoencephalitis.与原发性阿米巴脑膜脑炎相关的福氏耐格里变形虫蛋白质的鉴定。
Microbiology (Reading). 2017 Mar;163(3):322-332. doi: 10.1099/mic.0.000428. Epub 2017 Mar 23.
3
The 4-Aminomethylphenoxy-Benzoxaborole AN3057 as a Potential Treatment Option for Primary Amoebic Meningoencephalitis.4-氨甲基苯氧基苯并硼唑 AN3057 作为原发性阿米巴脑膜脑炎的潜在治疗选择。
Antimicrob Agents Chemother. 2023 Feb 16;67(2):e0150622. doi: 10.1128/aac.01506-22. Epub 2023 Jan 23.
4
Tackling infection owing to brain-eating amoeba.应对食脑变形虫感染。
Acta Trop. 2015 Feb;142:86-8. doi: 10.1016/j.actatropica.2014.11.004. Epub 2014 Nov 13.
5
The anti-amoebic potential of carboxamide derivatives containing sulfonyl or sulfamoyl moieties against brain-eating Naegleria fowleri.含磺酰基或氨磺酰基部分的羧酰胺衍生物对食脑福氏耐格里阿米巴的抗阿米巴潜力。
Parasitol Res. 2023 Nov;122(11):2539-2548. doi: 10.1007/s00436-023-07953-w. Epub 2023 Sep 4.
6
Diagnosis of the primary amoebic meningoencephalitis due to Naegleria fowleri.福氏耐格里阿米巴所致原发性阿米巴脑膜脑炎的诊断
Parasitol Int. 2005 Dec;54(4):219-21. doi: 10.1016/j.parint.2005.06.001.
7
The Effect of Different Environmental Conditions on the Viability of Naegleria fowleri Amoebae.不同环境条件对福氏耐格里阿米巴滋养体活力的影响。
J Eukaryot Microbiol. 2019 Sep;66(5):752-756. doi: 10.1111/jeu.12719. Epub 2019 Apr 7.
8
Pathogenesis of amoebic encephalitis: Are the amoebae being credited to an 'inside job' done by the host immune response?阿米巴性脑炎的发病机制：变形虫是否应归因于宿主免疫反应所做的“内部工作”？
Acta Trop. 2015 Aug;148:72-6. doi: 10.1016/j.actatropica.2015.04.022. Epub 2015 Apr 27.
9
Fighting with brain-eating amoeba: challenges and new insights to open a road for the treatment of Naegleria fowleri infection.与食脑变形虫作斗争：为治疗福氏耐格里阿米巴感染开辟道路的挑战与新见解
Expert Rev Anti Infect Ther. 2023 Jul-Dec;21(12):1277-1279. doi: 10.1080/14787210.2023.2263644. Epub 2023 Nov 24.
10
Primary Amoebic Meningoencephalitis: Neurochemotaxis and Neurotropic Preferences of Naegleria fowleri.原发性阿米巴脑膜脑炎：福氏耐格里变形虫的神经趋化性和神经嗜性。
ACS Chem Neurosci. 2016 Aug 17;7(8):1026-9. doi: 10.1021/acschemneuro.6b00197. Epub 2016 Jul 22.

本文引用的文献

1
Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials.季铵化合物（QACs）和离子液体（ILs）作为杀菌剂：从简单的防腐剂到可调抗菌剂。
Int J Mol Sci. 2021 Jun 24;22(13):6793. doi: 10.3390/ijms22136793.
2
Alkyl-carbon chain length of two distinct compounds and derivatives are key determinants of their anti-Acanthamoeba activities.两种不同化合物及其衍生物的烷基碳链长度是其抗棘阿米巴活性的关键决定因素。
Sci Rep. 2020 Apr 14;10(1):6420. doi: 10.1038/s41598-020-62934-8.
3
Biology and pathogenesis of Naegleria fowleri.
福氏耐格里阿米巴的生物学与发病机制。
Acta Trop. 2016 Dec;164:375-394. doi: 10.1016/j.actatropica.2016.09.009. Epub 2016 Sep 9.
4
AMP deaminase in vitro inhibition by xenobiotics A potential molecular method for risk assessment of synthetic nitro- and polycyclic musks, imidazolium ionic liquids and N-glucopyranosyl ammonium salts.外源化学物对 AMP 脱氨酶的体外抑制作用 一种用于评估合成硝基麝香和多环麝香、咪唑鎓离子液体以及 N-葡糖苷基铵盐风险的潜在分子方法
Environ Toxicol Pharmacol. 2005 Feb;19(2):291-6. doi: 10.1016/j.etap.2004.08.005.
5
Design of sustainable chemical products--the example of ionic liquids.可持续化学产品的设计——以离子液体为例。
Chem Rev. 2007 Jun;107(6):2183-206. doi: 10.1021/cr050942s.
6
Synthesis and properties of trigeminal tricationic ionic liquids.三叉三阳离子离子液体的合成与性质
Chemistry. 2007;13(11):3106-12. doi: 10.1002/chem.200601243.
7
Synthesis and anti-microbial activities of some pyridinium salts with alkoxymethyl hydrophobic group.一些带有烷氧基甲基疏水基团的吡啶鎓盐的合成及其抗菌活性
Eur J Med Chem. 2001 Nov-Dec;36(11-12):899-907.