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血清对恶性疟原虫裂殖体中裂殖子扩散的抑制作用:免疫状态的指标

Serum inhibition of merozoite dispersal from Plasmodium falciparum schizonts: indicator of immune status.

作者信息

Green T J, Morhardt M, Brackett R G, Jacobs R L

出版信息

Infect Immun. 1981 Mar;31(3):1203-8. doi: 10.1128/iai.31.3.1203-1208.1981.

Abstract

Specific immune serum was found to inhibit the dispersal of the merozoites from mature schizonts, thus interfering with their subsequent reinvasion of new host erythrocytes. This phenomenon is viewed as a protective mechanism against malaria which can be measured in vitro and reflects the immune status of the donor.

摘要

特异性免疫血清被发现可抑制裂殖子从成熟裂殖体中逸出,从而干扰其随后对新的宿主红细胞的再侵入。这种现象被视为一种针对疟疾的保护机制,可在体外进行检测,并反映供体的免疫状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9940/351443/fbeea9c8fa23/iai00167-0370-a.jpg

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