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冈比亚 12-23 月龄儿童五联疫苗和麻疹疫苗接种失败的决定因素。

Determinants of pentavalent and measles vaccination dropouts among children aged 12-23 months in The Gambia.

机构信息

Malaria Alert Center (MAC), Kamuzu University of Health Sciences (KUHeS), Privative Bag 360, Chichiri, Blantyre, 3, Malawi.

Academy of Medical Sciences (AMS), Malawi University of Science and Technology (MUST), P.O Box 5196, Limbe, Malawi.

出版信息

BMC Public Health. 2022 Mar 17;22(1):520. doi: 10.1186/s12889-022-12914-6.

Abstract

BACKGROUND

Every year, vaccination averts about 3 million deaths from vaccine-preventable diseases (VPDs). However, despite that immunization coverage is increasing globally, many children in developing countries are still dropping out of vaccination. Thus, the present study aimed to identify determinants of vaccination dropouts among children aged 12-23 months in The Gambia.

METHODS

The study utilized cross-sectional data obtained from the Gambia Demographic and Health Survey 2019-20 (GDHS). The percentage of children aged 12-23 months who dropped out from pentavalent and measles vaccination were calculated by (1) subtracting the third dose of pentavalent vaccine from the first dose of Pentavalent vaccine, and (2) subtracting the first dose of measles vaccine from the first dose Pentavalent vaccine. Generalized Estimating Equation models (GEE) were constructed to examine the risk factors of pentavalent and measles vaccinations dropout.

RESULTS

Approximately 7.0% and 4.0% of the 1,302 children aged 12-23 months had dropped out of measles and pentavalent vaccination respectively. The multivariate analyses showed that when caregivers attended fewer than four antenatal care sessions, when children had no health card or whose card was lost, and resided in urban areas increased the odds of pentavalent dropout. On the other hand, when women gave birth in home and other places, when children had no health card, and being an urban areas dweller increased the odds of measles dropout.

CONCLUSION

Tailored public health interventions towards urban residence and health education for all women during ANC are hereby recommended.

摘要

背景

每年,疫苗接种可预防约 300 万例疫苗可预防疾病(VPD)导致的死亡。然而,尽管全球免疫覆盖率正在提高,但许多发展中国家的儿童仍在疫苗接种中掉队。因此,本研究旨在确定冈比亚 12-23 个月儿童疫苗接种掉队的决定因素。

方法

本研究使用了 2019-20 年冈比亚人口与健康调查(GDHS)获得的横断面数据。通过以下方法计算了 12-23 个月儿童中放弃五联疫苗和麻疹疫苗接种的比例:(1)从第一剂五联疫苗中减去第三剂五联疫苗;(2)从第一剂五联疫苗中减去第一剂麻疹疫苗。构建广义估计方程模型(GEE)来检验五联和麻疹疫苗接种掉队的危险因素。

结果

约有 1302 名 12-23 个月的儿童中,有 7.0%和 4.0%分别放弃了麻疹和五联疫苗接种。多变量分析表明,当看护人参加少于四次产前护理时,当儿童没有健康卡或卡丢失,以及居住在城市地区时,会增加五联疫苗接种掉队的几率。另一方面,当妇女在家中或其他地方分娩时,当儿童没有健康卡,并且居住在城市地区时,会增加麻疹疫苗接种掉队的几率。

结论

建议针对城市居民制定有针对性的公共卫生干预措施,并在所有妇女的产前护理期间开展健康教育。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb49/8928633/d6e8eceda934/12889_2022_12914_Fig1_HTML.jpg

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