Department of Health Systems Planning and Management, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Department of Medical Laboratory Sciences, Denbya Primary Hospital, North Gondar, Gondar, Ethiopia.
PLoS One. 2021 Feb 8;16(2):e0246018. doi: 10.1371/journal.pone.0246018. eCollection 2021.
Vaccination is a proven tool in preventing and eradicating childhood infectious diseases. Each year, vaccination averts an estimated 2-3 million deaths from vaccine preventable diseases. Even though immunization coverage is increasing globally, many children in developing countries still dropout vaccination. The objective of this study was to identify determinants of vaccination dropout among children age 12-23 months in North Gondar, North west Ethiopia.
Community based unmatched case-control study was conducted in north Gondar from March 1-27, 2019 among 366 children age 12-23 months (92 cases and 274 controls). Multistage sampling was used for reaching to the community. Data were collected from mothers who had 12-23 months age children using a pretested structured face to face interview. Data were entered using Epi info v. 7 and exported to SPSS v. 20 for analysis. On multivariable logistic regression variables with P-value <0.05 at 95% CI were considered statistically significant.
Counseling for mothers about vaccination (AOR = 7.2, 95% CI: (2.93-17.5)); fear of vaccine side effects (AOR = 3.5, 95% CI: (1.56-8.12)); PNC attended (AOR = 3.6, 95% CI: (1.52-8.39)) and mothers not received tetanus toxoid vaccination (AOR = 2.4, 95% CI: (1.03-5.35)) were found risk factors of vaccination dropout.
Counseling on vaccination, fear of vaccine side effects, PNC attended and mothers' tetanus toxoid vaccination status during ANC visit were found risk factors. Management bodies and health workers need to consider "reaching every community" approach, Counsel every mother at any opportunity, and provide TT vaccination for all pregnant mothers helps to reduce vaccination dropout among children.
疫苗接种是预防和消除儿童传染病的有效工具。每年,疫苗接种可预防约 200 万至 300 万例疫苗可预防疾病死亡。尽管全球免疫覆盖率正在提高,但许多发展中国家的儿童仍未能完成疫苗接种。本研究旨在确定在埃塞俄比亚西北北贡德尔地区 12-23 个月儿童疫苗接种失败的决定因素。
2019 年 3 月 1 日至 27 日,在北贡德尔进行了一项基于社区的 12-23 个月儿童(92 例病例和 274 例对照)的非匹配病例对照研究。采用多阶段抽样方法进入社区。从有 12-23 个月龄儿童的母亲那里收集数据,使用经过预测试的面对面结构化访谈。使用 Epi info v.7 录入数据,并将数据导出到 SPSS v.20 进行分析。在多变量逻辑回归中,95%CI 中 P 值<0.05 的变量被认为具有统计学意义。
母亲接受疫苗接种咨询(AOR=7.2,95%CI:(2.93-17.5));担心疫苗副作用(AOR=3.5,95%CI:(1.56-8.12));参加过 PNC(AOR=3.6,95%CI:(1.52-8.39))和母亲未接种破伤风类毒素疫苗(AOR=2.4,95%CI:(1.03-5.35))是疫苗接种失败的危险因素。
疫苗接种咨询、担心疫苗副作用、参加 PNC 以及母亲在 ANC 期间接种破伤风类毒素疫苗的状况是疫苗接种失败的危险因素。管理机构和卫生工作者需要考虑“覆盖每个社区”的方法,在任何机会都要向每位母亲提供咨询,并为所有孕妇提供 TT 疫苗接种,这有助于减少儿童疫苗接种失败的情况。